ENSDARG00000016721


Danio rerio

Features
Gene ID: ENSDARG00000016721
  
Biological name :sdha
  
Synonyms : Q7ZVF3 / sdha / succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
  
Possible biological names infered from orthology : P31040 / Q8K2B3 / succinate dehydrogenase complex flavoprotein subunit A / Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 7276060
Gene end: 7291733
  
Corresponding Affymetrix probe sets: Dr.11239.1.S1_at (Zebrafish Array)   NM_200910_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000018027
NCBI entrez gene - 393884     See in Manteia.
RefSeq - NM_200910
RefSeq Peptide - NP_957204
swissprot - Q7ZVF3
ZFIN ID - ZDB-GENE-040426-874
Ensembl - ENSDARG00000016721
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SDHAENSGALG00000013167Gallus gallus
 SDHAENSG00000073578Homo sapiens
 SdhaENSMUSG00000021577Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003953  FAD-dependent oxidoreductase 2, FAD binding domain
 IPR011281  Succinate dehydrogenase, flavoprotein subunit
 IPR014006  Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
 IPR015939  Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal
 IPR023753  FAD/NAD(P)-binding domain
 IPR027477  Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006099 tricarboxylic acid cycle IBA
 biological_processGO:0006105 succinate metabolic process ISS
 biological_processGO:0006121 mitochondrial electron transport, succinate to ubiquinone IBA
 biological_processGO:0009061 anaerobic respiration IBA
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0022904 respiratory electron transport chain ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000104 succinate dehydrogenase activity ISS
 molecular_functionGO:0008177 succinate dehydrogenase (ubiquinone) activity IBA
 molecular_functionGO:0009055 electron transfer activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA


Pathways (from Reactome)
Pathway description
Citric acid cycle (TCA cycle)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000038608 sdhc / succinate dehydrogenase complex, subunit C, integral membrane protein / Q99643* / Q9CZB0* / succinate dehydrogenase complex subunit C*  / complex
 ENSDARG00000030139 sdhdb / Q68FN7 / succinate dehydrogenase complex, subunit D, integral membrane protein b / SDHD* / Q9CXV1* / O14521* / AP002884.3* / succinate dehydrogenase complex subunit D* / succinate d...  / complex
 ENSDARG00000075768 sdhb / A5PL98 / succinate dehydrogenase complex, subunit B, iron sulfur (Ip) / P21912* / succinate dehydrogenase complex iron sulfur subunit B*  / complex
 ENSDARG00000055712 sdhda / Q6DGM2 / succinate dehydrogenase complex, subunit D, integral membrane protein a / SDHD* / Q9CXV1* / O14521* / AP002884.3* / succinate dehydrogenase complex subunit D* / succinate d...  / complex






 

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