ENSDARG00000016771


Danio rerio

Features
Gene ID: ENSDARG00000016771
  
Biological name :tfa
  
Synonyms : tfa / transferrin-a
  
Possible biological names infered from orthology : 1300017J02Rik / Gm20425 / lactotransferrin / LTF / P02787 / P02788 / P08071 / Q921I1 / Q9DBD0 / RIKEN cDNA 1300017J02 gene / Serotransferrin / TF / transferrin / Trf
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 16780643
Gene end: 16794710
  
Corresponding Affymetrix probe sets: Dr.1889.1.S1_at (Zebrafish Array)   Dr.1889.2.A1_at (Zebrafish Array)   Dr.1889.2.A1_a_at (Zebrafish Array)   Dr.1889.2.A1_x_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000110220
Ensembl peptide - ENSDARP00000151155
Ensembl peptide - ENSDARP00000135247
Ensembl peptide - ENSDARP00000128522
Ensembl peptide - ENSDARP00000025702
Ensembl peptide - ENSDARP00000100241
NCBI entrez gene - 30255     See in Manteia.
RefSeq - NM_001291499
RefSeq Peptide - NP_001278428
swissprot - A0A0R4IHQ0
swissprot - F1R858
swissprot - Q6P3G0
swissprot - X1WE71
swissprot - E7FBJ1
swissprot - B8JL43
ZFIN ID - ZDB-GENE-980526-35
Ensembl - ENSDARG00000016771
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TFENSGALG00000006453Gallus gallus
 LTFENSG00000012223Homo sapiens
 TFENSG00000091513Homo sapiens
 Gm20425ENSMUSG00000090639Mus musculus
 LtfENSMUSG00000032496Mus musculus
 Q9DBD0ENSMUSG00000033688Mus musculus
 TrfENSMUSG00000032554Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
meltf / melanotransferrin / P08582* / Q9R0R1*ENSDARG0000007515935
zgc:172271ENSDARG0000001324032
otomp / Q0VIL3 / otolith matrix proteinENSDARG0000004030615


Protein motifs (from Interpro)
Interpro ID Name
 IPR001156  Transferrin-like domain
 IPR016357  Transferrin
 IPR018195  Transferrin family, iron binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006826 iron ion transport IMP
 biological_processGO:0009617 response to bacterium IDA
 biological_processGO:0042541 hemoglobin biosynthetic process IMP
 biological_processGO:0055072 iron ion homeostasis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Neutrophil degranulation
Metal sequestration by antimicrobial proteins
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Post-translational protein phosphorylation
Iron uptake and transport
Transferrin endocytosis and recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte hemoglobin complex decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr