ENSDARG00000017320


Danio rerio

Features
Gene ID: ENSDARG00000017320
  
Biological name :f11r.1
  
Synonyms : f11r.1 / F11 receptor, tandem duplicate 1
  
Possible biological names infered from orthology : F11R / F11 receptor / Junctional adhesion molecule A / O88792 / Q9Y624
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 29831195
Gene end: 29848772
  
Corresponding Affymetrix probe sets: Dr.4412.17.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000099952
NCBI entrez gene - 323696     See in Manteia.
swissprot - Q66I72
ZFIN ID - ZDB-GENE-030131-2416
Ensembl - ENSDARG00000017320
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F11RENSG00000158769Homo sapiens
 F11rENSMUSG00000038235Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
f11r.2 / F11 receptor, tandem duplicate 2 / F11R* / O88792* / Q9Y624* / F11 receptor* / Junctional adhesion molecule A *ENSDARG0000006811456
jam3a / junctional adhesion molecule 3a / JAM3* / Q9BX67* / Q9D8B7* / junctional adhesion molecule 3* / Junctional adhesion molecule C *ENSDARG0000011458932
jam3b / junctional adhesion molecule 3b / JAM3* / Q9BX67* / Q9D8B7* / junctional adhesion molecule 3* / Junctional adhesion molecule C *ENSDARG0000006179431
jam2b / junctional adhesion molecule 2b / JAM2* / P57087* / Q9JI59* / junctional adhesion molecule 2* / Junctional adhesion molecule B *ENSDARG0000007907130
jam2a / junctional adhesion molecule 2a / JAM2* / P57087* / Q9JI59* / junctional adhesion molecule 2* / Junctional adhesion molecule B *ENSDARG0000005899627


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0048534 hematopoietic or lymphoid organ development IMP
 biological_processGO:0048916 posterior lateral line development IMP
 biological_processGO:1902036 regulation of hematopoietic stem cell differentiation IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall
Integrin cell surface interactions
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
Tight junction interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000940 posterior lateral line neuromast posterior lateral line neuromast spatial pattern , abnormal
Show

 ZFA:0001157 posterior lateral line primordium posterior lateral line primordium shape , abnormal
posterior lateral line primordium organization quality , abnormal
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 ZFA:0005028 ventral wall of dorsal aorta ventral wall of dorsal aorta apoptotic process increased process quality , abnormal
ventral wall of dorsal aorta Notch signaling pathway decreased process quality , abnormal
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 ZFA:0005040 posterior lateral mesoderm posterior lateral mesoderm cell shape , abnormal
Show

 ZFA:0009065 endothelial cell endothelial cell Notch signaling pathway decreased process quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000021225 prkci / Q90XF2 / protein kinase C, iota / P41743* / Q62074*  / reaction / complex
 ENSDARG00000017320 f11r.1 / F11 receptor, tandem duplicate 1 / F11R* / O88792* / Q9Y624* / F11 receptor* / Junctional adhesion molecule A *  / reaction / complex
 ENSDARG00000068114 f11r.2 / F11 receptor, tandem duplicate 2 / F11R* / O88792* / Q9Y624* / F11 receptor* / Junctional adhesion molecule A *  / reaction / complex
 ENSDARG00000016939 itgb2 / integrin, beta 2 / Itgb2l* / P05107* / Q3UV74* / integrin subunit beta 2* / Integrin beta-2-like protein *  / reaction / complex






 

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