ENSDARG00000016939


Danio rerio

Features
Gene ID: ENSDARG00000016939
  
Biological name :itgb2
  
Synonyms : integrin, beta 2 / itgb2
  
Possible biological names infered from orthology : Integrin beta-2-like protein / integrin subunit beta 2 / Itgb2l / P05107 / Q3UV74
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 44961138
Gene end: 44983666
  
Corresponding Affymetrix probe sets: Dr.10706.1.A1_a_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000124433
NCBI entrez gene - 557797     See in Manteia.
RefSeq - XM_680920
swissprot - E7FCN5
ZFIN ID - ZDB-GENE-110411-4
Ensembl - ENSDARG00000016939
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ITGB2ENSGALG00000007511Gallus gallus
 ITGB2ENSG00000160255Homo sapiens
 Itgb2ENSMUSG00000000290Mus musculus
 Itgb2lENSMUSG00000000157Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
itgb1a / integrin, beta 1a / ITGB1* / P05556* / P09055* / Integrin beta-1 * / integrin subunit beta 1*ENSDARG0000007186344
itgb1b.1 / integrin, beta 1b.1ENSDARG0000005323243
itgb7 / integrin, beta 7 / P26010* / P26011* / integrin subunit beta 7*ENSDARG0000004431840
itgb3b / integrin beta 3b / ITGB3* / P05106* / O54890* / AC068234.1* / Integrin beta-3 * / integrin subunit beta 3*ENSDARG0000004507037
itgb3a / integrin beta 3a / ITGB3* / P05106* / AC068234.1* / integrin subunit beta 3*ENSDARG0000005676736
itgb5 / integrin, beta 5 / P18084* / integrin subunit beta 5*ENSDARG0000001294236
itgb6 / integrin, beta 6 / P18564* / Q9Z0T9* / integrin subunit beta 6*ENSDARG0000000249436
itgb4 / integrin, beta 4 / A2A863* / P16144* / integrin subunit beta 4*ENSDARG0000002850732
itgb1b.1 / itgb1b.2 / integrin, beta 1b.2ENSDARG0000002268931
itgb1b / integrin, beta 1b / ITGB1* / P05556* / integrin subunit beta 1*ENSDARG0000010448428
itgb8 / integrin, beta 8 / P26012* / integrin subunit beta 8*ENSDARG0000002822227
CABZ01058721.1 / ITGB1* / P05556* / integrin subunit beta 1*ENSDARG0000010992917
itgbl1 / integrin, beta-like 1 / O95965* / Q8VDV0* / integrin subunit beta like 1* / Integrin beta-like protein 1 *ENSDARG0000004098510


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR002369  Integrin beta subunit, VWA domain
 IPR012896  Integrin beta subunit, tail
 IPR014836  Integrin beta subunit, cytoplasmic domain
 IPR015439  Integrin beta-2 subunit
 IPR015812  Integrin beta subunit
 IPR016201  PSI domain
 IPR032695  Integrin domain superfamily
 IPR033760  Integrin beta N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000008969 fgb / fibrinogen beta chain / P02675* / Q8K0E8* / Fibrinogen beta chain Fibrinopeptide B Fibrinogen beta chain*  / complex / reaction
 ENSDARG00000020741 fga / fibrinogen alpha chain / E9PV24* / P02671* / Fibrinogen alpha chain Fibrinopeptide A Fibrinogen alpha chain*  / reaction / complex
 ENSDARG00000037281 fgg / fibrinogen gamma chain / P02679* / Q8VCM7*  / complex / reaction
 ENSDARG00000114589 jam3a / junctional adhesion molecule 3a / JAM3* / Q9BX67* / Q9D8B7* / junctional adhesion molecule 3* / Junctional adhesion molecule C *  / complex / reaction
 ENSDARG00000002956 si:dkey-32n7.4 / ITGAD* / ITGAM* / ITGAX* / Q13349* / P11215* / P20702* / Q9QXH4* / Q3V0T4* / integrin alpha M* / Integrin alpha-X * / Integrin alpha-D * / integrin subunit alpha X* / integ...  / complex
 ENSDARG00000068114 f11r.2 / F11 receptor, tandem duplicate 2 / F11R* / O88792* / Q9Y624* / F11 receptor* / Junctional adhesion molecule A *  / complex / reaction
 ENSDARG00000017320 f11r.1 / F11 receptor, tandem duplicate 1 / F11R* / O88792* / Q9Y624* / F11 receptor* / Junctional adhesion molecule A *  / complex / reaction






 

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