ENSDARG00000056767


Danio rerio

Features
Gene ID: ENSDARG00000056767
  
Biological name :itgb3a
  
Synonyms : integrin beta 3a / itgb3a
  
Possible biological names infered from orthology : AC068234.1 / Integrin beta-3 / integrin subunit beta 3 / ITGB3 / O54890 / P05106
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 19621034
Gene end: 19649535
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000014515
NCBI entrez gene - 564266     See in Manteia.
RefSeq - NM_001037235
RefSeq Peptide - NP_001032312
swissprot - B3DIV8
ZFIN ID - ZDB-GENE-071207-1
Ensembl - ENSDARG00000056767
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ITGB3ENSGALG00000000379Gallus gallus
 AC068234.1ENSG00000259753Homo sapiens
 ITGB3ENSG00000259207Homo sapiens
 Itgb3ENSMUSG00000020689Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
itgb3b / integrin beta 3b / ITGB3* / P05106* / O54890* / AC068234.1* / Integrin beta-3 * / integrin subunit beta 3*ENSDARG0000004507066
itgb5 / integrin, beta 5 / P18084* / integrin subunit beta 5*ENSDARG0000001294250
itgb6 / integrin, beta 6 / P18564* / Q9Z0T9* / integrin subunit beta 6*ENSDARG0000000249443
itgb1b.1 / integrin, beta 1b.1ENSDARG0000005323241
itgb1a / integrin, beta 1a / ITGB1* / P05556* / P09055* / Integrin beta-1 * / integrin subunit beta 1*ENSDARG0000007186340
itgb7 / integrin, beta 7 / P26010* / P26011* / integrin subunit beta 7*ENSDARG0000004431836
itgb2 / integrin, beta 2 / Itgb2l* / P05107* / Q3UV74* / integrin subunit beta 2* / Integrin beta-2-like protein *ENSDARG0000001693935
itgb4 / integrin, beta 4 / A2A863* / P16144* / integrin subunit beta 4*ENSDARG0000002850732
itgb1b.1 / itgb1b.2 / integrin, beta 1b.2ENSDARG0000002268930
itgb8 / integrin, beta 8 / P26012* / integrin subunit beta 8*ENSDARG0000002822229
itgb1b / integrin, beta 1b / ITGB1* / P05556* / integrin subunit beta 1*ENSDARG0000010448428
CABZ01058721.1 / ITGB1* / P05556* / integrin subunit beta 1*ENSDARG0000010992914
itgbl1 / integrin, beta-like 1 / O95965* / Q8VDV0* / integrin subunit beta like 1* / Integrin beta-like protein 1 *ENSDARG0000004098510


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR002369  Integrin beta subunit, VWA domain
 IPR012896  Integrin beta subunit, tail
 IPR014836  Integrin beta subunit, cytoplasmic domain
 IPR015812  Integrin beta subunit
 IPR016201  PSI domain
 IPR027068  Integrin beta-3 subunit
 IPR032695  Integrin domain superfamily
 IPR033760  Integrin beta N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007044 cell-substrate junction assembly IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0030334 regulation of cell migration IEA
 biological_processGO:0060055 angiogenesis involved in wound healing IEA
 biological_processGO:0070527 platelet aggregation IEA
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Elastic fibre formation
Molecules associated with elastic fibres
Integrin cell surface interactions
ECM proteoglycans
Integrin alphaIIb beta3 signaling
GRB2:SOS provides linkage to MAPK signaling for Integrins
p130Cas linkage to MAPK signaling for integrins
VEGFA-VEGFR2 Pathway
Signal transduction by L1
MAP2K and MAPK activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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