ENSDARG00000104484


Danio rerio

Features
Gene ID: ENSDARG00000104484
  
Biological name :itgb1b
  
Synonyms : integrin, beta 1b / itgb1b
  
Possible biological names infered from orthology : Integrin beta-1 / integrin subunit beta 1 / ITGB1 / P05556 / P09055
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 43577294
Gene end: 43583896
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000137182
swissprot - A0A0R4IR57
ZFIN ID - ZDB-GENE-030909-10
Ensembl - ENSDARG00000104484
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ITGB1ENSGALG00000007145Gallus gallus
 ITGB1ENSG00000150093Homo sapiens
 Itgb1ENSMUSG00000025809Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
itgb1a / integrin, beta 1a / ITGB1* / P05556* / P09055* / Integrin beta-1 * / integrin subunit beta 1*ENSDARG0000007186381
itgb1b.1 / integrin, beta 1b.1ENSDARG0000005323278
itgb1b.1 / itgb1b.2 / integrin, beta 1b.2ENSDARG0000002268950
itgb3b / integrin beta 3b / ITGB3* / P05106* / O54890* / AC068234.1* / Integrin beta-3 * / integrin subunit beta 3*ENSDARG0000004507043
itgb2 / integrin, beta 2 / Itgb2l* / P05107* / Q3UV74* / integrin subunit beta 2* / Integrin beta-2-like protein *ENSDARG0000001693941
itgb3a / integrin beta 3a / ITGB3* / P05106* / AC068234.1* / integrin subunit beta 3*ENSDARG0000005676741
itgb5 / integrin, beta 5 / P18084* / integrin subunit beta 5*ENSDARG0000001294239
itgb6 / integrin, beta 6 / P18564* / Q9Z0T9* / integrin subunit beta 6*ENSDARG0000000249438
itgb7 / integrin, beta 7 / P26010* / P26011* / integrin subunit beta 7*ENSDARG0000004431834
itgb4 / integrin, beta 4 / A2A863* / P16144* / integrin subunit beta 4*ENSDARG0000002850732
itgb8 / integrin, beta 8 / P26012* / integrin subunit beta 8*ENSDARG0000002822228
itgbl1 / integrin, beta-like 1 / O95965* / Q8VDV0* / integrin subunit beta like 1* / Integrin beta-like protein 1 *ENSDARG0000004098511
CABZ01058721.1 / ITGB1* / P05556* / integrin subunit beta 1*ENSDARG000001099291


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR002369  Integrin beta subunit, VWA domain
 IPR012896  Integrin beta subunit, tail
 IPR013111  EGF-like domain, extracellular
 IPR014836  Integrin beta subunit, cytoplasmic domain
 IPR015812  Integrin beta subunit
 IPR032695  Integrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0007368 determination of left/right symmetry IGI
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0042074 cell migration involved in gastrulation IMP
 biological_processGO:0045214 sarcomere organization IMP
 biological_processGO:0055013 cardiac muscle cell development IMP
 biological_processGO:0070121 Kupffer"s vesicle development IMP
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
Elastic fibre formation
Fibronectin matrix formation
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Cell surface interactions at the vascular wall
Basigin interactions
Molecules associated with elastic fibres
Integrin cell surface interactions
Laminin interactions
ECM proteoglycans
Signal transduction by L1
Localization of the PINCH-ILK-PARVIN complex to focal adhesions
MET activates PTK2 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle decreased volume , abnormal
Kupffers vesicle cilium decreased amount , abnormal
Kupffers vesicle unlumenized , abnormal
Kupffers vesicle epithelial cell apical-basal polarity , abnormal
Show

 ZFA:0000008 brain brain hemorrhagic , abnormal
Show

 ZFA:0000009 cardiac ventricle cardiac ventricle decreased volume , abnormal
Show

 ZFA:0000014 dorsal aorta dorsal aorta decreased diameter , abnormal
Show

 ZFA:0000023 forerunner cell group forerunner cell group spatial pattern , abnormal
forerunner cell group orientation forerunner cell group , abnormal
forerunner cell group circular , abnormal
forerunner cell group detached from forerunner cell group , abnormal
forerunner cell group pseudopodium direction , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000155 somite somite U-shaped , abnormal
Show

 ZFA:0000360 heart tube heart tube positional polarity , abnormal
Show

 ZFA:0000477 posterior cardinal vein posterior cardinal vein decreased diameter , abnormal
Show

 ZFA:0001114 head head morphology , abnormal
Show

 ZFA:0001117 post-vent region post-vent region undulate , abnormal
Show

 ZFA:0001261 ventricular system ventricular system increased accumulation cerebral spinal fluid , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel decreased amount , abnormal
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 ZFA:0005061 ventricular myocardium ventricular myocardium striated muscle thin filament decreased amount , abnormal
ventricular myocardium Z disc decreased amount , abnormal
Show

 ZFA:0005280 cardiac muscle cardiac muscle Z disc spatial pattern , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell Z disc disorganized , abnormal
cardiac muscle cell Z disc decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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