ENSMUSG00000000157


Mus musculus

Features
Gene ID: ENSMUSG00000000157
  
Biological name :Itgb2l
  
Synonyms : Integrin beta-2-like protein / Itgb2l / Q3UV74
  
Possible biological names infered from orthology : integrin subunit beta 2 / ITGB2 / P05107
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: C4
Gene start: 96422288
Gene end: 96443619
  
Corresponding Affymetrix probe sets: 10441178 (MoGene1.0st)   1433053_at (Mouse Genome 430 2.0 Array)   1433054_at (Mouse Genome 430 2.0 Array)   1449829_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000000161
Ensembl peptide - ENSMUSP00000109403
Ensembl peptide - ENSMUSP00000114497
NCBI entrez gene - 16415     See in Manteia.
MGI - MGI:1277979
RefSeq - XM_006522930
RefSeq - NM_008405
RefSeq - XM_006522925
RefSeq - XM_006522928
RefSeq - XM_006522929
RefSeq Peptide - NP_032431
swissprot - Q3UV74
swissprot - D3YXH8
Ensembl - ENSMUSG00000000157
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itgb2ENSDARG00000016939Danio rerio
 ITGB2ENSGALG00000007511Gallus gallus
 ITGB2ENSG00000160255Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Itgb2 / P05107* / integrin subunit beta 2*ENSMUSG0000000029058
Itgb7 / P26011 / Integrin beta-7 / P26010* / integrin subunit beta 7*ENSMUSG0000000128137
Itgb1 / P09055 / Integrin beta-1 / P05556* / integrin subunit beta 1*ENSMUSG0000002580935
Itgb3 / O54890 / Integrin beta-3 / P05106* / AC068234.1* / integrin subunit beta 3*ENSMUSG0000002068932
Itgb6 / Q9Z0T9 / Integrin beta-6 / P18564* / integrin subunit beta 6*ENSMUSG0000002697132
Itgb5 / integrin subunit beta 5 / P18084*ENSMUSG0000002281731
Itgb4 / A2A863 / Integrin beta-4 / P16144* / integrin subunit beta 4*ENSMUSG0000002075828
Itgb8 / integrin subunit beta 8 / P26012*ENSMUSG0000002532127
Itgbl1 / Q8VDV0 / Integrin beta-like protein 1 / O95965* / integrin subunit beta like 1*ENSMUSG0000003292516


Protein motifs (from Interpro)
Interpro ID Name
 IPR002369  Integrin beta subunit, VWA domain
 IPR012896  Integrin beta subunit, tail
 IPR015439  Integrin beta-2 subunit
 IPR015812  Integrin beta subunit
 IPR016201  PSI domain
 IPR032695  Integrin domain superfamily
 IPR033760  Integrin beta N-terminal
 IPR036349  Integrin beta tail domain superfamily
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030141 secretory granule IDA


Pathways (from Reactome)
Pathway description
Toll Like Receptor 4 (TLR4) Cascade
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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