ENSDARG00000017397


Danio rerio

Features
Gene ID: ENSDARG00000017397
  
Biological name :smarcc1a
  
Synonyms : smarcc1a / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a
  
Possible biological names infered from orthology : P97496 / Q92922 / SMARCC1 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 42423530
Gene end: 42461263
  
Corresponding Affymetrix probe sets: Dr.12644.1.S1_at (Zebrafish Array)   Dr.23828.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000103197
NCBI entrez gene - 403020     See in Manteia.
RefSeq - XM_003200246
swissprot - F1Q9K1
ZFIN ID - ZDB-GENE-080514-3
Ensembl - ENSDARG00000017397
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SMARCC1ENSGALG00000032642Gallus gallus
 Q92922ENSG00000173473Homo sapiens
 P97496ENSMUSG00000032481Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
smarcc2 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 / Q6PDG5* / Q8TAQ2* / SWI/SNF complex subunit SMARCC2 *ENSDARG0000007794659
smarcc1b / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b / P97496* / Q92922* / SMARCC1* / SWI/SNF related, matrix associated, actin depe...ENSDARG0000009891956


Protein motifs (from Interpro)
Interpro ID Name
 IPR001005  SANT/Myb domain
 IPR001357  BRCT domain
 IPR007526  SWIRM domain
 IPR009057  Homeobox-like domain superfamily
 IPR011991  ArsR-like helix-turn-helix domain
 IPR017884  SANT domain
 IPR032448  SMARCC, SWIRM-associated domain
 IPR032450  SMARCC, N-terminal
 IPR032451  SMARCC, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003007 heart morphogenesis IMP
 biological_processGO:0043044 ATP-dependent chromatin remodeling IEA
 biological_processGO:0060216 definitive hemopoiesis IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0016514 SWI/SNF complex IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000033647 Q5U379 / smarcb1a / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1a / Q9Z0H3* / Q12824* / SMARCB1* / SWI/SNF related, matrix associated, a...  / complex
 ENSDARG00000077946 smarcc2 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 / Q6PDG5* / Q8TAQ2* / SWI/SNF complex subunit SMARCC2 *  / complex
 ENSDARG00000008904 smarca2 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 / P51531*  / complex
 ENSDARG00000077226 smarca4a / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a / P51532* / Q3TKT4* / SMARCA4* / SWI/SNF related, matrix associated, actin depe...  / complex
 ENSDARG00000087646 runx1 / runt-related transcription factor 1 / Q01196*  / complex / reaction






 

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