ENSDARG00000008904


Danio rerio

Features
Gene ID: ENSDARG00000008904
  
Biological name :smarca2
  
Synonyms : smarca2 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  
Possible biological names infered from orthology : P51531
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 45138934
Gene end: 45284136
  
Corresponding Affymetrix probe sets: Dr.11436.1.S1_at (Zebrafish Array)   Dr.859.1.S1_at (Zebrafish Array)   NM_001044775_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000041411
Ensembl peptide - ENSDARP00000102553
Ensembl peptide - ENSDARP00000112752
Ensembl peptide - ENSDARP00000133519
NCBI entrez gene - 334032     See in Manteia.
RefSeq - NM_001044775
RefSeq - XM_009301625
RefSeq Peptide - NP_001038240
swissprot - F6NTB4
swissprot - A0A0R4IJ25
swissprot - F6PBX5
swissprot - Q1MTE3
ZFIN ID - ZDB-GENE-030131-5964
Ensembl - ENSDARG00000008904
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SMARCA2ENSGALG00000010164Gallus gallus
 P51531ENSG00000080503Homo sapiens
 Smarca2ENSMUSG00000024921Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
smarca4a / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a / P51532* / Q3TKT4* / SMARCA4* / SWI/SNF related, matrix associated, actin depe...ENSDARG0000007722674
SMARCA4 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 / P51532*ENSDARG0000010433970
si:dkey-226m8.10ENSDARG000000605788


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR001487  Bromodomain
 IPR001650  Helicase, C-terminal
 IPR006576  BRK domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014012  Helicase/SANT-associated domain
 IPR014978  Glutamine-Leucine-Glutamine, QLQ
 IPR018359  Bromodomain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029295  Snf2, ATP coupling domain
 IPR030088  SWI/SNF complex subunit SMARCA2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006338 chromatin remodeling IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016514 SWI/SNF complex IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016817 hydrolase activity, acting on acid anhydrides IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042393 histone binding IEA


Pathways (from Reactome)
Pathway description
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000033647 Q5U379 / smarcb1a / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1a / Q9Z0H3* / Q12824* / SMARCB1* / SWI/SNF related, matrix associated, a...  / complex
 ENSDARG00000077946 smarcc2 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 / Q6PDG5* / Q8TAQ2* / SWI/SNF complex subunit SMARCC2 *  / complex
 ENSDARG00000017397 smarcc1a / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a / P97496* / Q92922* / SMARCC1* / SWI/SNF related, matrix associated, actin depe...  / complex
 ENSDARG00000087646 runx1 / runt-related transcription factor 1 / Q01196*  / reaction / complex






 

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