ENSGALG00000010164


Gallus gallus

Features
Gene ID: ENSGALG00000010164
  
Biological name :SMARCA2
  
Synonyms : probable global transcription activator SNF2L2 / SMARCA2
  
Possible biological names infered from orthology : P51531 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 26328238
Gene end: 26435687
  
Corresponding Affymetrix probe sets: Gga.18784.1.S1_at (Chicken Array)   Gga.4606.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000016509
Ensembl peptide - ENSGALP00000050285
Ensembl peptide - ENSGALP00000046465
Ensembl peptide - ENSGALP00000043568
NCBI entrez gene - 396040     See in Manteia.
RefSeq - XM_015280070
RefSeq - XM_015280073
RefSeq - XM_015280072
RefSeq - NM_205139
RefSeq - XM_015280071
RefSeq Peptide - NP_990470
swissprot - E1C2F7
swissprot - A0A1D5NTB4
swissprot - A0A1D5PC01
Ensembl - ENSGALG00000010164
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smarca2ENSDARG00000008904Danio rerio
 P51531ENSG00000080503Homo sapiens
 Smarca2ENSMUSG00000024921Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR001487  Bromodomain
 IPR001650  Helicase, C-terminal
 IPR006576  BRK domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014012  Helicase/SANT-associated domain
 IPR014978  Glutamine-Leucine-Glutamine, QLQ
 IPR018359  Bromodomain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029295  Snf2, ATP coupling domain
 IPR030088  SWI/SNF complex subunit SMARCA2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006338 chromatin remodeling IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016514 SWI/SNF complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0045111 intermediate filament cytoskeleton IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016817 hydrolase activity, acting on acid anhydrides IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042393 histone binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000016022 RUNX1 / runt related transcription factor 1 / Q01196*  / complex / reaction
 ENSGALG00000005983 Q5ZK40 / SMARCB1 / SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 / Q12824* / Q9Z0H3*  / complex






 

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