ENSDARG00000019341


Danio rerio

Features
Gene ID: ENSDARG00000019341
  
Biological name :gpc1a
  
Synonyms : glypican 1a / gpc1a
  
Possible biological names infered from orthology : glypican 1 / GPC1 / P35052 / Q9QZF2
  
Species: Danio rerio
  
Chr. number: 22
Strand: 1
Band:
Gene start: 15507218
Gene end: 15548201
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000106138
swissprot - Q1LXM6
ZFIN ID - ZDB-GENE-051120-147
Ensembl - ENSDARG00000019341
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GPC1ENSGALG00000040316Gallus gallus
 GPC1ENSG00000063660Homo sapiens
 Gpc1ENSMUSG00000034220Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gpc1b / glypican 1b / GPC1* / P35052* / glypican 1*ENSDARG0000009058552
gpc6a / glypican 6a / GPC6* / Q9Y625* / glypican 6*ENSDARG0000010315642
gpc6b / glypican 6b / GPC6* / Q9Y625* / glypican 6*ENSDARG0000010421937
gpc4 / glypican 4 / O75487* / P51655*ENSDARG0000001547237
gpc2 / glypican 2 / Q8N158*ENSDARG0000010421723
gpc5a / glypican 5a / GPC5* / P78333* / glypican 5*ENSDARG0000010364723
gpc5b / glypican 5bENSDARG0000002458820
gpc3 / glypican 3 / P51654* / Q8CFZ4*ENSDARG0000003219919
CU467828.1ENSDARG0000007408216


Protein motifs (from Interpro)
Interpro ID Name
 IPR001863  Glypican
 IPR015502  Glypican-1
 IPR019803  Glypican, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009966 regulation of signal transduction IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0046658 anchored component of plasma membrane IEA
 molecular_functionGO:0043395 heparan sulfate proteoglycan binding IEA


Pathways (from Reactome)
Pathway description
A tetrasaccharide linker sequence is required for GAG synthesis
HS-GAG biosynthesis
HS-GAG degradation
Cell surface interactions at the vascular wall
Signaling by ROBO receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver decreased functionality , exacerbated
liver has fewer parts of type intrahepatic bile duct , exacerbated
Show

 ZFA:0000208 gall bladder gall bladder decreased size , abnormal
gall bladder lacks parts or has fewer parts of type cell , abnormal
Show

 ZFA:0001100 hepatic duct hepatic duct morphology , abnormal
Show

 ZFA:0005169 intrahepatic bile duct intrahepatic bile duct decreased functionality , abnormal
intrahepatic bile duct decreased length , exacerbated
Show

 ZFA:0005170 extrahepatic duct extrahepatic duct decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr