Manteia

ENSMUSG00000034220

Mus musculus

Features

Gene ID:	ENSMUSG00000034220

Biological name :	Gpc1

Synonyms :	glypican 1 / Gpc1 / Q9QZF2

Possible biological names infered from orthology :	P35052

Species:	Mus musculus

Chr. number:	1
Strand:	1
Band:	D
Gene start:	92831645
Gene end:	92860779

Corresponding Affymetrix probe sets:	10348653 (MoGene1.0st) 1417389_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000047199 NCBI entrez gene - 14733 See in Manteia. MGI - MGI:1194891 RefSeq - XM_011247925 RefSeq - NM_016696 RefSeq - XM_006529142 RefSeq Peptide - NP_057905 swissprot - Q9QZF2 swissprot - Q3U379 Ensembl - ENSMUSG00000034220

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Gpc6 / Q9R087 / glypican 6 / Q9Y625*	ENSMUSG00000058571	45
Gpc4 / P51655 / glypican 4 / O75487*	ENSMUSG00000031119	43
Gpc2 / Q8BKV1 / glypican 2 (cerebroglycan) / Q8N158* / glypican 2*	ENSMUSG00000029510	36
Gpc5 / Q8CAL5 / glypican 5 / P78333*	ENSMUSG00000022112	26
Gpc3 / Q8CFZ4 / glypican 3 / P51654*	ENSMUSG00000055653	22
Gm43720 / GPC2* / Q8N158* / glypican 2*	ENSMUSG00000106247	19

Protein motifs (from Interpro)

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0009966	regulation of signal transduction	IEA
biological_process	GO:0014037	Schwann cell differentiation	ISS
biological_process	GO:0030200	heparan sulfate proteoglycan catabolic process	ISS
biological_process	GO:0032288	myelin assembly	ISS
biological_process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	IDA
biological_process	GO:2001016	positive regulation of skeletal muscle cell differentiation	IEP
cellular_component	GO:0005576	extracellular region	ISO
cellular_component	GO:0005615	extracellular space	IEA
cellular_component	GO:0005654	nucleoplasm	IEA
cellular_component	GO:0005768	endosome	IEA
cellular_component	GO:0005796	Golgi lumen	TAS
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0005886	plasma membrane	ISO
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0031012	extracellular matrix	IEA
cellular_component	GO:0031225	anchored component of membrane	IEA
cellular_component	GO:0045121	membrane raft	IEA
cellular_component	GO:0046658	anchored component of plasma membrane	IEA
molecular_function	GO:0005507	copper ion binding	IEA
molecular_function	GO:0017134	fibroblast growth factor binding	IDA
molecular_function	GO:0043236	laminin binding	IDA
molecular_function	GO:0043395	heparan sulfate proteoglycan binding	IEA

Pathways (from Reactome)

Pathway description

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0001273	decreased metastatic potential		Show Allelic Composition: Tyrp1^rgsc101/Tyrp1^rgsc101 Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
MP:0002175	low brain weight	"lower than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Irf7^m1Btlr/Irf7⁺ Genetic Background: C57BL/6J-Irf7^m1Btlr
MP:0003638	abnormal response/metabolism to endogenous compounds	"altered ability or inability to metabolize or respond to substances normally present in the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Tyrp1^rgsc101/Tyrp1^rgsc101 Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000031558	Slit2 / Q9R1B9 / slit guidance ligand 2 / O94813*	/ reaction / complex

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr