ENSDARG00000021905


Danio rerio

Features
Gene ID: ENSDARG00000021905
  
Biological name :derl1
  
Synonyms : derl1 / derlin 1
  
Possible biological names infered from orthology : Q99J56 / Q9BUN8
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 25643445
Gene end: 25663846
  
Corresponding Affymetrix probe sets: Dr.1920.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000036613
NCBI entrez gene - 406753     See in Manteia.
swissprot - F1Q4W3
ZFIN ID - ZDB-GENE-040426-2793
Ensembl - ENSDARG00000021905
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DERL1ENSGALG00000033950Gallus gallus
 DERL1ENSG00000136986Homo sapiens
 Derl1ENSMUSG00000022365Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
derl3 / derlin 3 / Q96Q80* / Q9D8K3* / Mus musculus Der1-like domain family, member 3 (Derl3), transcript variant 2, mRNA.*ENSDARG0000003387131
derl2 / derlin 2 / Q9GZP9*ENSDARG0000004240131


Protein motifs (from Interpro)
Interpro ID Name
 IPR007599  Derlin
 IPR022764  Peptidase S54, rhomboid domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
ABC-family proteins mediated transport
N-glycan trimming in the ER and Calnexin/Calreticulin cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye morphology , abnormal
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 ZFA:0000114 heart heart decreased functionality , abnormal
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 ZFA:0000339 digestive system digestive system swollen , abnormal
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 ZFA:0001094 whole organism whole organism dead , abnormal
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 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton morphology , abnormal
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 ZFA:0001655 pericardial cavity pericardial cavity swollen , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000021905 derl1 / derlin 1 / Q99J56* / Q9BUN8*  / complex






 

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© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr