ENSDARG00000042401


Danio rerio

Features
Gene ID: ENSDARG00000042401
  
Biological name :derl2
  
Synonyms : derl2 / derlin 2
  
Possible biological names infered from orthology : Q8BNI4 / Q9GZP9
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 58996765
Gene end: 59012599
  
Corresponding Affymetrix probe sets: Dr.11772.1.A1_at (Zebrafish Array)   Dr.20414.1.A1_s_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000062174
NCBI entrez gene - 554093     See in Manteia.
swissprot - Q4VBS8
ZFIN ID - ZDB-GENE-050522-90
Ensembl - ENSDARG00000042401
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DERL2ENSGALG00000041844Gallus gallus
 DERL2ENSG00000072849Homo sapiens
 Derl2ENSMUSG00000018442Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
derl3 / derlin 3 / Q96Q80* / Q9D8K3* / Mus musculus Der1-like domain family, member 3 (Derl3), transcript variant 2, mRNA.*ENSDARG0000003387180
derl1 / derlin 1 / Q99J56* / Q9BUN8*ENSDARG0000002190534


Protein motifs (from Interpro)
Interpro ID Name
 IPR007599  Derlin
 IPR022764  Peptidase S54, rhomboid domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
ABC-family proteins mediated transport
Hedgehog ligand biogenesis
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000020008 vcp / Q7ZU99 / valosin containing protein / P55072* / Q01853*  / complex
 ENSDARG00000004581 sel1l / sel-1 suppressor of lin-12-like (C. elegans) / Q9UBV2* / Q9Z2G6* / SEL1L ERAD E3 ligase adaptor subunit*  / complex
 ENSDARG00000017842 syvn1 / synovial apoptosis inhibitor 1, synoviolin / Q86TM6* / synoviolin 1*  / complex






 

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contact: otassy@igbmc.fr