ENSDARG00000017842


Danio rerio

Features
Gene ID: ENSDARG00000017842
  
Biological name :syvn1
  
Synonyms : synovial apoptosis inhibitor 1, synoviolin / syvn1
  
Possible biological names infered from orthology : Q86TM6 / synoviolin 1
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 26452740
Gene end: 26465729
  
Corresponding Affymetrix probe sets: Dr.3405.1.S1_at (Zebrafish Array)   NM_212735_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000116575
NCBI entrez gene - 335226     See in Manteia.
RefSeq - NM_212735
RefSeq Peptide - NP_997900
swissprot - A5PMC1
ZFIN ID - ZDB-GENE-030131-7166
Ensembl - ENSDARG00000017842
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SYVN1ENSG00000162298Homo sapiens
 Syvn1ENSMUSG00000024807Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
amfra / autocrine motility factor receptor a / AMFR* / Q9UKV5* / Q9R049* / E3 ubiquitin-protein ligase AMFR * / autocrine motility factor receptor*ENSDARG0000002021817
rnf145b / ring finger protein 145b / Q5SWK7* / Q96MT1* / RNF145* / ring finger protein 145*ENSDARG0000003237314
amfrb / autocrine motility factor receptor b / AMFR* / Q9UKV5* / Q9R049* / E3 ubiquitin-protein ligase AMFR * / autocrine motility factor receptor*ENSDARG0000010557814
rnf145a / ring finger protein 145a / Q5SWK7* / Q96MT1* / RNF145* / ring finger protein 145*ENSDARG0000000260913
zmp:0000000662ENSDARG0000005682913
rnf139 / ring finger protein 139 / Q8WU17*ENSDARG0000003692912


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR032832  E3 ubiquitin-protein ligase synoviolin/Hrd1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IEA
 cellular_componentGO:0000836 Hrd1p ubiquitin ligase complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
Hedgehog ligand biogenesis
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000042401 derl2 / derlin 2 / Q9GZP9*  / complex
 ENSDARG00000004581 sel1l / sel-1 suppressor of lin-12-like (C. elegans) / Q9UBV2* / Q9Z2G6* / SEL1L ERAD E3 ligase adaptor subunit*  / complex
 ENSDARG00000017842 syvn1 / synovial apoptosis inhibitor 1, synoviolin / Q86TM6* / synoviolin 1*  / complex
 ENSDARG00000020008 vcp / Q7ZU99 / valosin containing protein / P55072* / Q01853*  / complex






 

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