ENSDARG00000020218


Danio rerio

Features
Gene ID: ENSDARG00000020218
  
Biological name :amfra
  
Synonyms : amfra / autocrine motility factor receptor a
  
Possible biological names infered from orthology : AMFR / autocrine motility factor receptor / E3 ubiquitin-protein ligase AMFR / Q9R049 / Q9UKV5
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 36197733
Gene end: 36217563
  
Corresponding Affymetrix probe sets: Dr.19542.1.A1_at (Zebrafish Array)   Dr.24648.1.A1_s_at (Zebrafish Array)   Dr.24648.1.A1_x_at (Zebrafish Array)   Dr.6936.1.A1_at (Zebrafish Array)   NM_213163_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000002529
Ensembl peptide - ENSDARP00000106624
NCBI entrez gene - 406442     See in Manteia.
RefSeq - NM_213163
RefSeq - XM_009298211
RefSeq Peptide - NP_998328
swissprot - F1QB30
ZFIN ID - ZDB-GENE-040426-2190
Ensembl - ENSDARG00000020218
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AMFRENSGALG00000003107Gallus gallus
 AMFRENSG00000159461Homo sapiens
 AmfrENSMUSG00000031751Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
amfrb / autocrine motility factor receptor b / AMFR* / Q9UKV5* / Q9R049* / E3 ubiquitin-protein ligase AMFR * / autocrine motility factor receptor*ENSDARG0000010557837
syvn1 / synovial apoptosis inhibitor 1, synoviolin / Q86TM6* / synoviolin 1*ENSDARG0000001784217
rnf139 / ring finger protein 139 / Q8WU17*ENSDARG0000003692913
rnf145b / ring finger protein 145b / Q5SWK7* / Q96MT1* / RNF145* / ring finger protein 145*ENSDARG0000003237313
rnf145a / ring finger protein 145a / Q5SWK7* / Q96MT1* / RNF145* / ring finger protein 145*ENSDARG0000000260913
zmp:0000000662ENSDARG0000005682912


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR003892  Ubiquitin system component Cue
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IBA
 biological_processGO:0034976 response to endoplasmic reticulum stress IMP
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA
 molecular_functionGO:1990381 ubiquitin-specific protease binding IBA


Pathways (from Reactome)
Pathway description
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism absent , abnormal
whole organism decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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