ENSGALG00000041844


Gallus gallus

Features
Gene ID: ENSGALG00000041844
  
Biological name :DERL2
  
Synonyms : DERL2 / derlin 2
  
Possible biological names infered from orthology : Q8BNI4 / Q9GZP9
  
Species: Gallus gallus
  
Chr. number: 19
Strand: 1
Band:
Gene start: 3389364
Gene end: 3393485
  
Corresponding Affymetrix probe sets: Gga.12732.1.S1_at (Chicken Array)   Gga.6232.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050515
Ensembl peptide - ENSGALP00000063974
Ensembl peptide - ENSGALP00000059999
Ensembl peptide - ENSGALP00000057135
NCBI entrez gene - 417498     See in Manteia.
RefSeq - XM_015295984
swissprot - A0A1L1RYP8
swissprot - A0A1L1RMK4
swissprot - A0A1D5PW06
swissprot - A0A1D5PCM6
Ensembl - ENSGALG00000041844
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 derl2ENSDARG00000042401Danio rerio
 DERL2ENSG00000072849Homo sapiens
 Derl2ENSMUSG00000018442Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DERL3 / derlin 3 / Q96Q80* / Q9D8K3* / Mus musculus Der1-like domain family, member 3 (Derl3), transcript variant 2, mRNA.*ENSGALG0000000599481
DERL1 / derlin 1 / Q99J56* / Q9BUN8*ENSGALG0000003395035


Protein motifs (from Interpro)
Interpro ID Name
 IPR007599  Derlin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001967 suckling behavior IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IEA
 biological_processGO:0030970 retrograde protein transport, ER to cytosol IEA
 biological_processGO:1904153 negative regulation of retrograde protein transport, ER to cytosol IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005785 signal recognition particle receptor complex IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 cellular_componentGO:0048500 signal recognition particle IEA


Pathways (from Reactome)
Pathway description
ABC-family proteins mediated transport
Hedgehog ligand biogenesis
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000010581 SEL1L / SEL1L ERAD E3 ligase adaptor subunit / Q9UBV2* / Q9Z2G6* / sel-1 suppressor of lin-12-like (C. elegans)*  / complex
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction






 

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