ENSGALG00000033950


Gallus gallus

Features
Gene ID: ENSGALG00000033950
  
Biological name :DERL1
  
Synonyms : DERL1 / derlin 1
  
Possible biological names infered from orthology : Q99J56 / Q9BUN8
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 138011465
Gene end: 138026622
  
Corresponding Affymetrix probe sets: GgaAffx.11528.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000063733
Ensembl peptide - ENSGALP00000045550
NCBI entrez gene - 420350     See in Manteia.
RefSeq - NM_001006350
RefSeq Peptide - NP_001006350
swissprot - Q5ZMF9
swissprot - A0A1L1RY27
Ensembl - ENSGALG00000033950
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 derl1ENSDARG00000021905Danio rerio
 DERL1ENSG00000136986Homo sapiens
 Derl1ENSMUSG00000022365Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DERL2 / derlin 2 / Q8BNI4* / Q9GZP9*ENSGALG0000004184433
DERL3 / derlin 3 / Q96Q80* / Q9D8K3* / Mus musculus Der1-like domain family, member 3 (Derl3), transcript variant 2, mRNA.*ENSGALG0000000599430


Protein motifs (from Interpro)
Interpro ID Name
 IPR007599  Derlin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IEA
 biological_processGO:0030970 retrograde protein transport, ER to cytosol IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination IEA
 biological_processGO:0031648 protein destabilization IEA
 biological_processGO:0032092 positive regulation of protein binding IEA
 biological_processGO:0034620 cellular response to unfolded protein IEA
 biological_processGO:0036503 ERAD pathway IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0071712 ER-associated misfolded protein catabolic process IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005785 signal recognition particle receptor complex IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 cellular_componentGO:0036502 Derlin-1-VIMP complex IEA
 cellular_componentGO:0036513 Derlin-1 retrotranslocation complex IEA
 cellular_componentGO:0048500 signal recognition particle IEA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0042288 MHC class I protein binding IEA
 molecular_functionGO:0051117 ATPase binding IEA
 molecular_functionGO:1990381 ubiquitin-specific protease binding IEA


Pathways (from Reactome)
Pathway description
ABC-family proteins mediated transport
N-glycan trimming in the ER and Calnexin/Calreticulin cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000033950 DERL1 / derlin 1 / Q99J56* / Q9BUN8*  / complex






 

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