ENSDARG00000029830


Danio rerio

Features
Gene ID: ENSDARG00000029830
  
Biological name :myf6
  
Synonyms : myf6 / myogenic factor 6 / Q6VNZ9
  
Possible biological names infered from orthology : P15375 / P23409
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 21717793
Gene end: 21720943
  
Corresponding Affymetrix probe sets: DrAffx.2.28.A1_at (Zebrafish Array)   DrAffx.2.28.S1_at (Zebrafish Array)   NM_001003982_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000040265
NCBI entrez gene - 404208     See in Manteia.
RefSeq - NM_001003982
RefSeq Peptide - NP_001003982
swissprot - B3DK75
swissprot - Q6VNZ9
ZFIN ID - ZDB-GENE-040309-2
Ensembl - ENSDARG00000029830
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYF6ENSGALG00000010936Gallus gallus
 MYF6ENSG00000111046Homo sapiens
 Myf6ENSMUSG00000035923Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
myog / myogenin / P12979* / P15173*ENSDARG0000000943843
myod1 / Q90477 / myogenic differentiation 1 / P10085* / P15172* / Myoblast determination protein 1 *ENSDARG0000003011033
myf5 / myogenic factor 5 / P13349* / P24699*ENSDARG0000000727731


Protein motifs (from Interpro)
Interpro ID Name
 IPR002546  Myogenic basic muscle-specific protein
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0007519 skeletal muscle tissue development IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IBA
 biological_processGO:0045663 positive regulation of myoblast differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048743 positive regulation of skeletal muscle fiber development IBA
 biological_processGO:1901741 positive regulation of myoblast fusion IBA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IBA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
CDO in myogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000155 somite somite U-shaped , abnormal
somite myofibril misaligned with somite myofibril, abnormal
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 ZFA:0001115 trunk trunk curved ventral , abnormal
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 ZFA:0001462 somite border somite border amorphous , abnormal
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 ZFA:0009244 primary motor neuron primary motor neuron axon morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000009418 mef2cb / myocyte enhancer factor 2cb / MEF2C* / Q8CFN5* / Q06413* / myocyte enhancer factor 2C* / Mus musculus myocyte enhancer factor 2C (Mef2c), transcript variant 14, mRNA.*  / reaction / complex






 

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