ENSDARG00000030110


Danio rerio

Features
Gene ID: ENSDARG00000030110
  
Biological name :myod1
  
Synonyms : myod1 / myogenic differentiation 1 / Q90477
  
Possible biological names infered from orthology : Myoblast determination protein 1 / P10085 / P15172
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 31421253
Gene end: 31423493
  
Corresponding Affymetrix probe sets: Dr.5693.1.S1_at (Zebrafish Array)   NM_131262_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000009713
NCBI entrez gene - 30513     See in Manteia.
RefSeq - NM_131262
RefSeq Peptide - NP_571337
swissprot - Q90477
ZFIN ID - ZDB-GENE-980526-561
Ensembl - ENSDARG00000030110
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYOD1ENSGALG00000006216Gallus gallus
 MYOD1ENSG00000129152Homo sapiens
 Myod1ENSMUSG00000009471Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
myf5 / myogenic factor 5 / P13349* / P24699*ENSDARG0000000727740
myf6 / Q6VNZ9 / myogenic factor 6 / P15375* / P23409*ENSDARG0000002983029
myog / myogenin / P12979* / P15173*ENSDARG0000000943828


Protein motifs (from Interpro)
Interpro ID Name
 IPR002546  Myogenic basic muscle-specific protein
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR022032  Myogenic determination factor 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002074 extraocular skeletal muscle development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0007519 skeletal muscle tissue development IGI
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IGI
 biological_processGO:0043282 pharyngeal muscle development IMP
 biological_processGO:0043966 histone H3 acetylation ISS
 biological_processGO:0043967 histone H4 acetylation ISS
 biological_processGO:0045663 positive regulation of myoblast differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0048741 skeletal muscle fiber development IMP
 biological_processGO:0048743 positive regulation of skeletal muscle fiber development IBA
 biological_processGO:0055002 striated muscle cell development IGI
 biological_processGO:0071392 cellular response to estradiol stimulus ISS
 biological_processGO:1901741 positive regulation of myoblast fusion IBA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0001047 core promoter binding ISS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031490 chromatin DNA binding ISS
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
CDO in myogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000155 somite somite nucleus apoptotic , abnormal
somite morphology , abnormal
Show

 ZFA:0000204 esophagus esophagus skeletal muscle cell poorly differentiated , abnormal
Show

 ZFA:0000328 cephalic musculature cephalic musculature decreased amount , abnormal
cephalic musculature aplastic , abnormal
Show

 ZFA:0001094 whole organism whole organism lacks all parts of type skeletal muscle , abnormal
whole organism movement quality , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head lacks parts or has fewer parts of type cephalic musculature , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage decreased length , abnormal
ceratohyal cartilage chondrocyte morphology , abnormal
ceratohyal cartilage chondrocyte decreased size , abnormal
Show

 ZFA:0001652 head muscle head muscle poorly differentiated , abnormal
head muscle hypoplastic , abnormal
Show

 ZFA:0005145 muscle muscle aplastic , abnormal
muscle apoptotic , abnormal
muscle disorganized , abnormal
muscle sarcomere disoriented , abnormal
muscle sarcomere disorganized , abnormal
Show

 ZFA:0009084 chondrocyte chondrocyte stacked , abnormal
Show

 ZFA:0009116 slow muscle cell slow muscle cell muscle fiber development decreased process quality , abnormal
Show

 ZFA:0009117 fast muscle cell fast muscle cell absent , abnormal
fast muscle cell muscle fiber development decreased process quality , abnormal
fast muscle cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000009418 mef2cb / myocyte enhancer factor 2cb / MEF2C* / Q8CFN5* / Q06413* / myocyte enhancer factor 2C* / Mus musculus myocyte enhancer factor 2C (Mef2c), transcript variant 14, mRNA.*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr