ENSDARG00000031116


Danio rerio

Features
Gene ID: ENSDARG00000031116
  
Biological name :dnal4a
  
Synonyms : dnal4a / dynein, axonemal, light chain 4a
  
Possible biological names infered from orthology : DNAL4 / dynein axonemal light chain 4 / Dynein light chain 4, axonemal / O96015 / Q9DCM4
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 24511959
Gene end: 24518496
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000115737
NCBI entrez gene - 445209     See in Manteia.
RefSeq - NM_001003603
RefSeq Peptide - NP_001003603
swissprot - Q6DEH4
ZFIN ID - ZDB-GENE-040801-122
Ensembl - ENSDARG00000031116
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DNAL4ENSGALG00000043451Gallus gallus
 DNAL4ENSG00000100246Homo sapiens
 Dnal4ENSMUSG00000022420Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dnal4b / dynein, axonemal, light chain 4b / DNAL4* / Q9DCM4* / O96015* / dynein axonemal light chain 4* / Dynein light chain 4, axonemal *ENSDARG0000008884192
dynll1 / dynein, light chain, LC8-type 1 / P63168* / P63167* / BC048507* / cDNA sequence BC048507* / Dynein light chain 1, cytoplasmic *ENSDARG0000005845428
dynll2a / dynein, light chain, LC8-type 2a / Q9D0M5* / DYNLL2* / Q96FJ2* / dynein light chain LC8-type 2* / Dynein light chain 2, cytoplasmic *ENSDARG0000006979026
dynll2b / dynein, light chain, LC8-type 2b / DYNLL2* / Q96FJ2* / dynein light chain LC8-type 2*ENSDARG0000000517226
si:dkeyp-51b9.3 / DYNLL1* / P63167* / P63168* / BC048507* / cDNA sequence BC048507* / dynein light chain LC8-type 1* / Dynein light chain 1, cytoplasmic *ENSDARG0000009237916


Protein motifs (from Interpro)
Interpro ID Name
 IPR001372  Dynein light chain, type 1/2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007017 microtubule-based process IEA
 biological_processGO:2000582 positive regulation of ATP-dependent microtubule motor activity, plus-end-directed IBA
 cellular_componentGO:0030286 dynein complex IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IBA
 molecular_functionGO:0008574 ATP-dependent microtubule motor activity, plus-end-directed IBA
 molecular_functionGO:0045505 dynein intermediate chain binding IBA
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
Retrograde neurotrophin signalling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000045618 clta / clathrin, light chain A / P09496*  / reaction
 ENSDARG00000090716 cltcb / clathrin, heavy chain b (Hc) / CLTC* / Q00610* / clathrin heavy chain*  / reaction
 ENSDARG00000026967 ap2s1 / adaptor-related protein complex 2, sigma 1 subunit / P53680* / P62743* / AP-2 complex subunit sigma *  / reaction
 ENSDARG00000035152 ap2b1 / adaptor-related protein complex 2, beta 1 subunit / P63010* / Q9DBG3* / AP-2 complex subunit beta *  / reaction
 ENSDARG00000033899 ap2m1b / adaptor-related protein complex 2, mu 1 subunit, b / AP2M1* / Q96CW1* / P84091* / AP-2 complex subunit mu * / adaptor related protein complex 2 mu 1 subunit*  / reaction
 ENSDARG00000002790 Q6NWK2 / ap2m1a / ap2m1b / adaptor-related protein complex 2, mu 1 subunit, b / AP2M1* / Q96CW1* / P84091* / AP-2 complex subunit mu * / adaptor related protein complex 2 mu 1 subunit*  / reaction
 ENSDARG00000004586 ntrk1 / neurotrophic tyrosine kinase, receptor, type 1 / P04629* / Q3UFB7* / neurotrophic receptor tyrosine kinase 1* / High affinity nerve growth factor receptor *  / reaction
 ENSDARG00000058961 ngfa / O73797 / nerve growth factor a (beta polypeptide) / NGF* / P01139* / P01138* / nerve growth factor* / Beta-nerve growth factor *  / reaction
 ENSDARG00000014050 ngfb / Q6YBR5 / nerve growth factor b (beta polypeptide) / NGF* / P01138* / P01139* / nerve growth factor* / Beta-nerve growth factor *  / reaction
 ENSDARG00000023600 sh3gl2a / SH3 domain containing GRB2 like 2a, endophilin A1 / Q99962* / SH3GL2* / Q62420* / SH3-domain GRB2-like 2* / SH3 domain containing GRB2 like 2, endophilin A1*  / reaction






 

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