ENSDARG00000031316


Danio rerio

Features
Gene ID: ENSDARG00000031316
  
Biological name :six6b
  
Synonyms : six6b / SIX homeobox 6b
  
Possible biological names infered from orthology : O95475 / Q9QZ28 / sine oculis-related homeobox 6 / SIX6 / SIX homeobox 6
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 20531002
Gene end: 20533865
  
Corresponding Affymetrix probe sets: Dr.11125.1.A1_at (Zebrafish Array)   NM_001020585_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000110487
NCBI entrez gene - 553611     See in Manteia.
RefSeq - NM_001020585
RefSeq Peptide - NP_001018421
swissprot - Q5TYZ2
ZFIN ID - ZDB-GENE-050522-308
Ensembl - ENSDARG00000031316
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SIX6ENSGALG00000020359Gallus gallus
 SIX6ENSG00000184302Homo sapiens
 Six6ENSMUSG00000021099Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
six6a / SIX homeobox 6a / SIX6* / Q9QZ28* / O95475* / SIX homeobox 6* / sine oculis-related homeobox 6*ENSDARG0000002518792
six3a / SIX homeobox 3a / SIX3* / Q62233* / O95343* / SIX homeobox 3* / Homeobox protein SIX3 *ENSDARG0000005800880
six3b / SIX homeobox 3b / SIX3* / Q62233* / O95343* / SIX homeobox 3* / Homeobox protein SIX3 *ENSDARG0000005487976
six7 / SIX homeobox 7ENSDARG0000007010770
six2a / SIX homeobox 2a / SIX2* / Q9NPC8* / Q62232* / SIX homeobox 2* / Homeobox protein SIX2 *ENSDARG0000005800457
six1b / Q6NZ04 / SIX homeobox 1b / SIX1* / Q62231* / Q15475* / SIX homeobox 1* / Homeobox protein SIX1 *ENSDARG0000002647355
six2b / SIX homeobox 2b / SIX2* / Q9NPC8* / Q62232* / SIX homeobox 2* / Homeobox protein SIX2 *ENSDARG0000005487854
six1a / Q6DHF9 / SIX homeobox 1a / SIX1* / Q62231* / Q15475* / SIX homeobox 1* / Homeobox protein SIX1 *ENSDARG0000003930454
six4b / SIX homeobox 4b / SIX4* / Q9UIU6* / Q61321* / SIX homeobox 4* / Homeobox protein SIX4 *ENSDARG0000003198349
six4a / SIX homeobox 4a / SIX4* / Q9UIU6* / Q61321* / SIX homeobox 4* / Homeobox protein SIX4 *ENSDARG0000000469548
six9 / SIX homeobox 9ENSDARG0000006840747
six5 / SIX homeobox 5 / P70178* / Q8N196* / Homeobox protein SIX5 *ENSDARG0000006840642


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR031701  Homeobox protein SIX1, N-terminal SD domain
 IPR032947  Homeobox protein SIX6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0035736 cell proliferation involved in compound eye morphogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000035 lens lens immature , abnormal
lens cellularity , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye hypoplastic , abnormal
eye immature , abnormal
eye increased amount , abnormal
Show

 ZFA:0000152 retina retina proliferative , abnormal
retina cell proliferation process quality , abnormal
Show

 ZFA:0000435 cranial nerve II cranial nerve II decreased thickness , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased pigmentation , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton shortened , abnormal
mandibular arch skeleton decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr