ENSDARG00000037514


Danio rerio

Features
Gene ID: ENSDARG00000037514
  
Biological name :hdac3
  
Synonyms : hdac3 / histone deacetylase 3
  
Possible biological names infered from orthology : O15379
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 12178915
Gene end: 12205865
  
Corresponding Affymetrix probe sets: Dr.9053.1.A1_at (Zebrafish Array)   Dr.9920.2.A1_s_at (Zebrafish Array)   NM_200990_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000054625
Ensembl peptide - ENSDARP00000137825
NCBI entrez gene - 393965     See in Manteia.
RefSeq - NM_200990
RefSeq Peptide - NP_957284
swissprot - F1RCG9
swissprot - A0A0R4IPZ3
ZFIN ID - ZDB-GENE-040426-847
Ensembl - ENSDARG00000037514
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HDAC3ENSGALG00000002634Gallus gallus
 HDAC3ENSG00000171720Homo sapiens
 Hdac3ENSMUSG00000024454Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hdac1 / histone deacetylase 1 / O09106* / Q13547* / Gm10093*ENSDARG0000001542759
hdac8 / histone deacetylase 8 / Q8VH37* / Q9BY41*ENSDARG0000000302136
hdac12 / histone deacetylase 12ENSDARG0000010142218
hdac11 / histone deacetylase 11 / Q96DB2*ENSDARG0000008757317


Protein motifs (from Interpro)
Interpro ID Name
 IPR000286  Histone deacetylase family
 IPR003084  Histone deacetylase
 IPR023801  Histone deacetylase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016575 histone deacetylation IEA
 biological_processGO:0070932 histone H3 deacetylation IEA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003714 transcription corepressor activity ISS
 molecular_functionGO:0004407 histone deacetylase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver decreased size , abnormal
liver aplastic , abnormal
Show

 ZFA:0000671 horizontal myoseptum horizontal myoseptum decreased distribution , abnormal
Show

 ZFA:0000940 posterior lateral line neuromast posterior lateral line neuromast decreased amount , abnormal
posterior lateral line neuromast position , abnormal
posterior lateral line neuromast decreased distribution , abnormal
Show

 ZFA:0001094 whole organism whole organism quality , abnormal
Show

 ZFA:0001114 head head circular , abnormal
head decreased size , abnormal
Show

 ZFA:0001157 posterior lateral line primordium posterior lateral line primordium absent , abnormal
posterior lateral line primordium decreased distribution , abnormal
posterior lateral line primordium morphology , abnormal
posterior lateral line primordium apoptotic process increased occurrence , abnormal
posterior lateral line primordium cell proliferation decreased process quality , abnormal
posterior lateral line primordium shape , abnormal
posterior lateral line primordium size , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel decreased size , abnormal
Show

 ZFA:0005227 protoneuromast protoneuromast decreased distribution , abnormal
protoneuromast decreased amount , abnormal
Show

 ZFA:0009367 neuromast hair cell neuromast hair cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr