Manteia - Molecule gene

ENSMUSG00000024454

Mus musculus

Features

Gene ID:	ENSMUSG00000024454

Biological name :	Hdac3

Synonyms :	Hdac3 / histone deacetylase 3

Possible biological names infered from orthology :	O15379

Species:	Mus musculus

Chr. number:	18
Strand:	-1
Band:	B3
Gene start:	37935844
Gene end:	37954988

Corresponding Affymetrix probe sets:	10458461 (MoGene1.0st) 1426437_s_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000037981 NCBI entrez gene - 15183 See in Manteia. MGI - MGI:1343091 RefSeq - NM_010411 RefSeq Peptide - NP_034541 swissprot - Q3UM33 Ensembl - ENSMUSG00000024454

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
hdac3	ENSDARG00000037514	Danio rerio
HDAC3	ENSGALG00000002634	Gallus gallus
HDAC3	ENSG00000171720	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Hdac1 / O09106 / Histone deacetylase 1 / Q13547*	ENSMUSG00000028800	60
Gm10093 / HDAC1* / Q13547* / histone deacetylase 1*	ENSMUSG00000061062	59
Hdac2 / histone deacetylase 2 / Q92769*	ENSMUSG00000019777	58
Hdac8 / Q8VH37 / Histone deacetylase 8 / Q9BY41*	ENSMUSG00000067567	35
Hdac11 / Q91WA3 / Histone deacetylase 11 / Q96DB2*	ENSMUSG00000034245	18

Protein motifs (from Interpro)

Interpro ID	Name
IPR000286	Histone deacetylase family
IPR003084	Histone deacetylase
IPR023696	Ureohydrolase domain superfamily
IPR023801	Histone deacetylase domain
IPR037138	Histone deacetylase domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000122	negative regulation of transcription by RNA polymerase II	IEA
biological_process	GO:0001934	positive regulation of protein phosphorylation	IEA
biological_process	GO:0006325	chromatin organization	IEA
biological_process	GO:0006351	transcription, DNA-templated	IEA
biological_process	GO:0006355	regulation of transcription, DNA-templated	IEA
biological_process	GO:0006476	protein deacetylation	IEA
biological_process	GO:0016575	histone deacetylation	IEA
biological_process	GO:0031647	regulation of protein stability	IEA
biological_process	GO:0032008	positive regulation of TOR signaling	IEA
biological_process	GO:0042993	obsolete positive regulation of transcription factor import into nucleus	IEA
biological_process	GO:0045892	negative regulation of transcription, DNA-templated	IEA
biological_process	GO:0045944	positive regulation of transcription by RNA polymerase II	IEA
biological_process	GO:0046329	negative regulation of JNK cascade	IEA
biological_process	GO:0051225	spindle assembly	IEA
biological_process	GO:0070932	histone H3 deacetylation	IEA
biological_process	GO:0071498	cellular response to fluid shear stress	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005654	nucleoplasm	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005794	Golgi apparatus	IEA
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0005876	spindle microtubule	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0017053	transcriptional repressor complex	IEA
molecular_function	GO:0003682	chromatin binding	IEA
molecular_function	GO:0003714	transcription corepressor activity	IEA
molecular_function	GO:0004407	histone deacetylase activity	IEA
molecular_function	GO:0008134	transcription factor binding	IEA
molecular_function	GO:0016787	hydrolase activity	IEA
molecular_function	GO:0019899	enzyme binding	IEA
molecular_function	GO:0030332	cyclin binding	IEA
molecular_function	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)	IEA
molecular_function	GO:0033558	protein deacetylase activity	IEA
molecular_function	GO:0042826	histone deacetylase binding	IEA
molecular_function	GO:0046872	metal ion binding	IEA
molecular_function	GO:0051059	NF-kappaB binding	IEA

Pathways (from Reactome)

Pathway description

HDACs deacetylate histones

Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000182	increased circulating LDL cholesterol level	"greater than average concentration in the blood of low density lipoprotein, which normally transports cholesterol to tissues other than the liver" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0000189	hypoglycemia	"low levels of plasma glucose in the circulating blood; this generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0000266	abnormal cardiac morphology	"anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Hdac3^tm1.2Eno/Hdac3^tm1.2Eno Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0000313	abnormal cell death	"anomalous cessation of function at the cellular level" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0000352	decreased cell proliferation	"less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0000599	enlarged liver	"larger than average size of the liver" [J:65146]	Show Allelic Composition: Alox12b^tm1.1Krie/Alox12b^tm1.1Krie Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * BALB/cJ * C57BL/6 Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0000603	pale liver	"liver lacking normal coloration, often refers to bloodless condition" [J:18048]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0000607	abnormal hepatocyte morphology	"malformation of the main structural component of the liver; these are specialized epithelial cells normally organize into interconnected plates called lobules" [J:23170, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Alox12b^tm1.1Krie/Alox12b^tm1.1Krie Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * BALB/cJ * C57BL/6 Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0001547	abnormal lipid level	"anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Hdac3^tm1.2Eno/Hdac3^tm1.2Eno Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0001552	increased circulating triglyceride level	"higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0001625	cardiac hypertrophy	"an increase in size of the cardiac tissue, not due to increased cell number " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Hdac3^tm1.2Eno/Hdac3^tm1.2Eno Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0001695	abnormal gastrulation	"anomalous development and invagination of the embryonic germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: F2^tm1Jld/F2^tm1Sjd Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
MP:0002078	abnormal glucose homeostasis	"anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0002083	premature death	"death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Hdac3^tm1.2Eno/Hdac3^tm1.2Eno Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: Hdac3^tm1.1Laz/Hdac3^tm1.1Laz,Tg(Fabp4-cre)1Rev/0 Genetic Background: involves: C57BL/6
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Kl^tm1.2Tel/Kl^tm1.2Tel Genetic Background: involves: C57BL/6 * FVB/N
MP:0002628	fatty liver	"an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Alox12b^tm1.1Krie/Alox12b^tm1.1Krie Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * BALB/cJ * C57BL/6 Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA Allelic Composition: Hdac3^tm1.1Laz/Hdac3^tm1.1Laz Genetic Background: involves: C57BL/6
MP:0002696	decreased circulating glucagon level	"lower than normal blood concentration of this peptide hormone" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0002727	decreased circulating insulin level	"less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0002753	dilated left ventricle	"an expansion in the volume of the lower left chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Hdac3^tm1.2Eno/Hdac3^tm1.2Eno Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0002801	abnormal long-term recognition memory	"defects in long-term memory for objects that is consolidated over hours and days after training." [CFG:Center for Functional Genomics , Northwestern University]	Show Allelic Composition: Foxm1^tm1Rhc/Foxm1^tm1Rhc,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129 * 129X1/SvJ * C57BL/6
MP:0002833	increased heart weight	"greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]	Show Allelic Composition: Hdac3^tm1.2Eno/Hdac3^tm1.2Eno Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0002941	increased circulating alanine transaminase level	"increased concentration in the blood of this enzyme, which transfers amino groups from l-alanine to 2 ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0002981	increased liver weight	"a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator]	Show Allelic Composition: Alox12b^tm1.1Krie/Alox12b^tm1.1Krie Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * BALB/cJ * C57BL/6 Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0003077	abnormal cell cycle	"failure to progress or abnormal progression through the stages of of the cell cycle" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91266]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Tg(CAG-cre/Esr1)5Amc/0 Genetic Background:* involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N
MP:0003893	increased hepatocyte proliferation	"anomalous growth and reproduction of hepatocyte cells of the liver" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0003982	increased cholesterol level	"greater than normal concentration in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0005150	cachexia	"general weight loss and wasting occurring in the course of chronic disease" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Hdac3^tm1.1Laz/Hdac3^tm1.1Laz,Tg(Fabp4-cre)1Rev/0 Genetic Background: involves: C57BL/6
MP:0005178	increased total circulating cholesterol level	"greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0005317	increased triglyceride level	"higher than normal concentration of triacylglycerols " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Hdac3^tm1.2Eno/Hdac3^tm1.2Eno Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0005406	abnormal heart size	"change from the norm in the physical magnitude of the cardiac muscle or any of its component structures" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Hdac3^tm1.2Eno/Hdac3^tm1.2Eno Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0005439	decreased glycogen level	"less than the normal concentration of this readily converted carbohydrate reserve, found in most tissues of the body, especially liver and muscle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Alox12b^tm1.1Krie/Alox12b^tm1.1Krie Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * BALB/cJ * C57BL/6 Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0005598	decreased ventricle muscle contractility	"reduced ability of the heart ventricle muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]	Show Allelic Composition: Hdac3^tm1.2Eno/Hdac3^tm1.2Eno Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0005608	cardiac interstitial fibrosis	"formation of fibrous tissue within the interstices of the heart as a result of repair or a reactive process" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]	Show Allelic Composition: Hdac3^tm1.2Eno/Hdac3^tm1.2Eno Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0005621	abnormal cell physiology	"aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0006035	abnormal mitochondrial morphology	"anomalous structure of the mitochondria" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Hdac3^tm1.2Eno/Hdac3^tm1.2Eno Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0008058	abnormal DNA repair	"any anomaly in the process of restoring DNA after damage or replication error" [GO:0006281]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Tg(CAG-cre/Esr1)5Amc/0 Genetic Background:* involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N
MP:0009355	increased liver triglyceride level	"higher than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0010025	decreased total body fat amount	"less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0010954	abnormal cellular respiration	"anomaly in the enzymatic release of energy from organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration)" [GO:0045333]	Show Allelic Composition: Hdac3^tm1.2Eno/Hdac3^tm1.2Eno Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0011086	partial postnatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Hdac3^tm1.1Laz/Hdac3^tm1.1Laz,Tg(Fabp4-cre)1Rev/0 Genetic Background: involves: C57BL/6
MP:0011092	complete embryonic lethality	"death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA Allelic Composition: Hdac3^tm1.2Eno/Hdac3^tm1.2Eno Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0011635	abnormal mitochondrial crista morphology	"Any of the inward folds of the mitochondrial inner membrane; crista number, extent, and shape differ in mitochondria from different tissues and organisms; crista appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found; the shape can vary with the respiratory state of the mitochondria" [GO:0030061]	Show Allelic Composition: Hdac3^tm1.2Eno/Hdac3^tm1.2Eno Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0013501	increased fibroblast apoptosis	"increase in the timing or the number of fibroblast cells undergoing programmed cell death" [MGI:csmith]	Show Allelic Composition: Hdac3^tm1Swh/Hdac3^tm1.1Swh,Tg(CAG-cre/Esr1)5Amc/0 Genetic Background:* involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr