ENSDARG00000037905


Danio rerio

Features
Gene ID: ENSDARG00000037905
  
Biological name :cacna1aa
  
Synonyms : cacna1aa / calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a
  
Possible biological names infered from orthology : CACNA1A / calcium voltage-gated channel subunit alpha1 A / O00555 / P97445 / Voltage-dependent P/Q-type calcium channel subunit alpha-1A
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 33773156
Gene end: 33901483
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000118181
Ensembl peptide - ENSDARP00000023232
Ensembl peptide - ENSDARP00000116045
swissprot - E9QJF6
swissprot - Q5RHB1
swissprot - Q5RHB2
ZFIN ID - ZDB-GENE-040724-26
Ensembl - ENSDARG00000037905
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 O00555ENSG00000141837Homo sapiens
 P97445ENSMUSG00000034656Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cacna1ab / calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b / O00555* / P97445* / CACNA1A* / calcium voltage-gated channel subunit alpha1 A* / Voltage-dependent P/Q-type ca...ENSDARG0000000692375
cacna1bb / calcium channel, voltage-dependent, N type, alpha 1B subunit, b / O55017* / Q00975* / CACNA1B* / calcium voltage-gated channel subunit alpha1 B* / Voltage-dependent N-type calciu...ENSDARG0000007929558
cacna1ba / calcium channel, voltage-dependent, N type, alpha 1B subunit, a / O55017* / Q00975* / CACNA1B* / calcium voltage-gated channel subunit alpha1 B* / Voltage-dependent N-type calciu...ENSDARG0000002173557
cacna1eb / calcium channel, voltage-dependent, R type, alpha 1E subunit b / Q15878* / CACNA1E* / calcium voltage-gated channel subunit alpha1 E*ENSDARG0000009561449
cacna1ea / calcium channel, voltage-dependent, R type, alpha 1E subunit a / Q15878* / CACNA1E* / calcium voltage-gated channel subunit alpha1 E*ENSDARG0000006234640
cacna1c / calcium channel, voltage-dependent, L type, alpha 1C subunit / Q01815* / Q13936* / calcium voltage-gated channel subunit alpha1 C* / Voltage-dependent L-type calcium channel subun...ENSDARG0000000839835
cacna1da / calcium channel, voltage-dependent, L type, alpha 1D subunit, a / Q01668* / CACNA1D* / calcium voltage-gated channel subunit alpha1 D*ENSDARG0000010277334
cacna1fb / calcium channel, voltage-dependent, L type, alpha 1F subunit / O60840* / CACNA1F* / calcium voltage-gated channel subunit alpha1 F*ENSDARG0000002368332
cacna1sa / calcium channel, voltage-dependent, L type, alpha 1S subunit, a / Q13698* / CACNA1S* / calcium voltage-gated channel subunit alpha1 S*ENSDARG0000002945731
cacna1sb / calcium channel, voltage-dependent, L type, alpha 1S subunit, b / Q13698* / CACNA1S* / calcium voltage-gated channel subunit alpha1 S*ENSDARG0000004255231
nalcn / sodium leak channel, non-selective / Q8IZF0*ENSDARG0000000183516
cacna1fa / calcium channel, voltage-dependent, L type, alpha 1F subunit a / O60840* / CACNA1F* / calcium voltage-gated channel subunit alpha1 F*ENSDARG0000001093313
cacna1db / calcium channel, voltage-dependent, L type, alpha 1D subunit, b / Q01668* / CACNA1D* / calcium voltage-gated channel subunit alpha1 D*ENSDARG000001106429
FO082780.1 / O60840* / CACNA1F* / calcium voltage-gated channel subunit alpha1 F*ENSDARG000001155287
cacna1db / calcium channel, voltage-dependent, L type, alpha 1D subunit, b / Q01668* / CACNA1D* / calcium voltage-gated channel subunit alpha1 D*ENSDARG000001156036


Protein motifs (from Interpro)
Interpro ID Name
 IPR002077  Voltage-dependent calcium channel, alpha-1 subunit
 IPR005448  Voltage-dependent calcium channel, P/Q-type, alpha-1 A
 IPR005821  Ion transport domain
 IPR014873  Voltage-dependent calcium channel, alpha-1 subunit, IQ domain
 IPR031649  Voltage-dependent L-type calcium channel, IQ-associated domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0086010 membrane depolarization during action potential IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0005891 voltage-gated calcium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005245 voltage-gated calcium channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0008331 high voltage-gated calcium channel activity IBA


Pathways (from Reactome)
Pathway description
Presynaptic depolarization and calcium channel opening
Regulation of insulin secretion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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