ENSDARG00000102773


Danio rerio

Features
Gene ID: ENSDARG00000102773
  
Biological name :cacna1da
  
Synonyms : cacna1da / calcium channel, voltage-dependent, L type, alpha 1D subunit, a
  
Possible biological names infered from orthology : CACNA1D / calcium voltage-gated channel subunit alpha1 D / Q01668 / Q99246 / Voltage-dependent L-type calcium channel subunit alpha-1D
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 36793473
Gene end: 36963988
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000134024
Ensembl peptide - ENSDARP00000137557
NCBI entrez gene - 403310     See in Manteia.
RefSeq - NM_203484
RefSeq - XM_021479582
RefSeq Peptide - NP_982351
swissprot - A0A0R4IQX8
swissprot - A0A0R4IK24
ZFIN ID - ZDB-GENE-030616-135
Ensembl - ENSDARG00000102773
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 O73700ENSGALG00000005332Gallus gallus
 Q01668ENSG00000157388Homo sapiens
 Q99246ENSMUSG00000015968Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cacna1c / calcium channel, voltage-dependent, L type, alpha 1C subunit / Q01815* / Q13936* / calcium voltage-gated channel subunit alpha1 C* / Voltage-dependent L-type calcium channel subun...ENSDARG0000000839866
cacna1fb / calcium channel, voltage-dependent, L type, alpha 1F subunit / O60840* / CACNA1F* / calcium voltage-gated channel subunit alpha1 F*ENSDARG0000002368364
cacna1sa / calcium channel, voltage-dependent, L type, alpha 1S subunit, a / Q13698* / CACNA1S* / calcium voltage-gated channel subunit alpha1 S*ENSDARG0000002945752
cacna1sb / calcium channel, voltage-dependent, L type, alpha 1S subunit, b / Q13698* / CACNA1S* / calcium voltage-gated channel subunit alpha1 S*ENSDARG0000004255250
cacna1ab / calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b / O00555* / P97445* / CACNA1A* / calcium voltage-gated channel subunit alpha1 A* / Voltage-dependent P/Q-type ca...ENSDARG0000000692337
cacna1ba / calcium channel, voltage-dependent, N type, alpha 1B subunit, a / O55017* / Q00975* / CACNA1B* / calcium voltage-gated channel subunit alpha1 B* / Voltage-dependent N-type calciu...ENSDARG0000002173537
cacna1bb / calcium channel, voltage-dependent, N type, alpha 1B subunit, b / O55017* / Q00975* / CACNA1B* / calcium voltage-gated channel subunit alpha1 B* / Voltage-dependent N-type calciu...ENSDARG0000007929537
cacna1aa / calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a / O00555* / CACNA1A* / calcium voltage-gated channel subunit alpha1 A*ENSDARG0000003790537
cacna1eb / calcium channel, voltage-dependent, R type, alpha 1E subunit b / Q15878* / CACNA1E* / calcium voltage-gated channel subunit alpha1 E*ENSDARG0000009561435
cacna1ea / calcium channel, voltage-dependent, R type, alpha 1E subunit a / Q15878* / CACNA1E* / calcium voltage-gated channel subunit alpha1 E*ENSDARG0000006234627
cacna1fa / calcium channel, voltage-dependent, L type, alpha 1F subunit a / O60840* / CACNA1F* / calcium voltage-gated channel subunit alpha1 F*ENSDARG0000001093321
nalcn / sodium leak channel, non-selective / Q8IZF0*ENSDARG0000000183518
cacna1db / calcium channel, voltage-dependent, L type, alpha 1D subunit, b / Q01668* / CACNA1D* / calcium voltage-gated channel subunit alpha1 D*ENSDARG0000011064218
FO082780.1 / O60840* / CACNA1F* / calcium voltage-gated channel subunit alpha1 F*ENSDARG0000011552810
cacna1db / calcium channel, voltage-dependent, L type, alpha 1D subunit, b / Q01668* / CACNA1D* / calcium voltage-gated channel subunit alpha1 D*ENSDARG000001156039


Protein motifs (from Interpro)
Interpro ID Name
 IPR002077  Voltage-dependent calcium channel, alpha-1 subunit
 IPR005446  Voltage-dependent calcium channel, L-type, alpha-1 subunit
 IPR005452  Voltage-dependent calcium channel, L-type, alpha-1D subunit
 IPR005821  Ion transport domain
 IPR014873  Voltage-dependent calcium channel, alpha-1 subunit, IQ domain
 IPR031649  Voltage-dependent L-type calcium channel, IQ-associated domain
 IPR031688  Voltage-gated calcium channel subunit alpha, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0050808 synapse organization IGI
 biological_processGO:0050885 neuromuscular process controlling balance IMP
 biological_processGO:0050910 detection of mechanical stimulus involved in sensory perception of sound IMP
 biological_processGO:0050974 detection of mechanical stimulus involved in sensory perception IMP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005891 voltage-gated calcium channel complex IEA
 cellular_componentGO:0009925 basal plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0097470 ribbon synapse IDA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005245 voltage-gated calcium channel activity ISS
 molecular_functionGO:0005262 calcium channel activity IEA


Pathways (from Reactome)
Pathway description
Regulation of insulin secretion
Phase 0 - rapid depolarisation
Phase 2 - plateau phase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism unbalanced , abnormal
whole organism decreased behavioural activity , abnormal
whole organism circling , abnormal
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 ZFA:0009367 neuromast hair cell neuromast hair cell synapse organization process quality , abnormal
neuromast hair cell cellular response to mechanical stimulus process quality , abnormal
neuromast hair cell ribbon synapse morphology , abnormal
neuromast hair cell physical object quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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