ENSDARG00000037946


Danio rerio

Features
Gene ID: ENSDARG00000037946
  
Biological name :prl
  
Synonyms : prl / prolactin
  
Possible biological names infered from orthology : Mus musculus prolactin family 2, subfamily c, member 4 (Prl2c4), mRNA. / O35256 / O35257 / P01236 / P04095 / P04768 / P04769 / P06879 / P09586 / Prl2a1 / Prl2b1 / Prl2c1 / Prl2c2 / Prl2c3 / Prl2c5 / Prl3a1 / Prl3b1 / Prl3c1 / Prl3d1 / Prl3d2 / Prl3d3 / Prl4a1 / Prl5a1 / Prl6a1 / Prl7b1 / Prl7c1 / Prl7d1 / Prolactin-2C2 / Prolactin-2C5 / Prolactin-7B1 / prolactin family 2, subfamily a, member 1 / prolactin family 2, subfamily b, member 1 / Prolactin family 2, subfamily c, member 1 / prolactin family 3, subfamily a, member 1 / prolactin family 3, subfamily b, member 1 / prolactin family 3, subfamily c, member 1 / prolactin family 3, subfamily d, member 1 / prolactin family 3, subfamily d, member 3 / prolactin family 4, subfamily a, member 1 / prolactin family 5, subfamily a, member 1 / prolactin family 6, subfamily a, member 1 / prolactin family 7, subfamily c, member 1 / prolactin family 7, subfamily d, member 1 / Q8CGZ9 / Q9CRB5 / Q9DAZ2 / Q9JHK0 / Q9JII2 / Q9JLV9 / Q9QUN5
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 32341917
Gene end: 32345900
  
Corresponding Affymetrix probe sets: Dr.24254.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000055298
NCBI entrez gene - 791526     See in Manteia.
RefSeq - NM_181437
RefSeq Peptide - NP_852102
swissprot - F1R0Y2
ZFIN ID - ZDB-GENE-030513-1
Ensembl - ENSDARG00000037946
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prlENSGALG00000012671Gallus gallus
 PRLENSG00000172179Homo sapiens
 O35256ENSMUSG00000005891Mus musculus
 O35257ENSMUSG00000069259Mus musculus
 P04095ENSMUSG00000079092Mus musculus
 P04768ENSMUSG00000056457Mus musculus
 P04769ENSMUSG00000021348Mus musculus
 P09586ENSMUSG00000038891Mus musculus
 PrlENSMUSG00000021342Mus musculus
 Prl2a1ENSMUSG00000022886Mus musculus
 Prl2b1ENSMUSG00000069258Mus musculus
 Prl2c1ENSMUSG00000062551Mus musculus
 Prl2c5ENSMUSG00000055360Mus musculus
 Prl3a1ENSMUSG00000038883Mus musculus
 Prl3c1ENSMUSG00000017922Mus musculus
 Prl3d1ENSMUSG00000057170Mus musculus
 Prl3d2ENSMUSG00000062737Mus musculus
 Prl3d3ENSMUSG00000062201Mus musculus
 Prl5a1ENSMUSG00000017064Mus musculus
 Prl7b1ENSMUSG00000021347Mus musculus
 Prl7c1ENSMUSG00000060738Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prl2 / prolactin 2ENSDARG0000001874431


Protein motifs (from Interpro)
Interpro ID Name
 IPR001400  Somatotropin/prolactin
 IPR009079  Four-helical cytokine-like, core
 IPR018116  Somatotropin hormone, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0033555 multicellular organismal response to stress IEP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005179 hormone activity IEA


Pathways (from Reactome)
Pathway description
Prolactin receptor signaling
Growth hormone receptor signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain apoptotic , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct vH ionocyte decreased amount , abnormal
Show

 ZFA:0000151 pronephros pronephros decreased amount , abnormal
Show

 ZFA:0000354 gill gill increased amount , abnormal
gill vH ionocyte increased amount , abnormal
gill NCC ionocyte decreased amount , abnormal
gill sodium(1+) decreased amount , abnormal
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 ZFA:0001094 whole organism whole organism decreased amount , abnormal
whole organism curved , abnormal
whole organism edematous , abnormal
whole organism swollen , abnormal
whole organism shortened , abnormal
whole organism life span , ameliorated
whole organism decreased life span , abnormal
whole organism chloride amount , ameliorated
whole organism chloride decreased amount , abnormal
whole organism sodium(1+) amount , ameliorated
whole organism sodium(1+) decreased amount , abnormal
whole organism potassium(1+) amount , ameliorated
whole organism potassium(1+) decreased amount , abnormal
Show

 ZFA:0001114 head head increased amount , abnormal
head decreased amount , abnormal
Show

 ZFA:0001200 corpuscles of Stannius corpuscles of Stannius decreased amount , abnormal
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 ZFA:0001620 pronephric proximal convoluted tubule pronephric proximal convoluted tubule vH ionocyte decreased amount , abnormal
Show

 ZFA:0001621 pronephric proximal straight tubule pronephric proximal straight tubule vH ionocyte decreased amount , abnormal
Show

 ZFA:0001678 immature eye immature eye apoptotic , abnormal
Show

 ZFA:0005326 NaK ionocyte NaK ionocyte increased amount , abnormal
Show

 ZFA:0009198 xanthophore xanthophore decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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