ENSMUSG00000079092


Mus musculus

Features
Gene ID: ENSMUSG00000079092
  
Biological name :Prl2c2
  
Synonyms : P04095 / Prl2c2 / Prolactin-2C2
  
Possible biological names infered from orthology : P01236 / PRL / prolactin
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: A1
Gene start: 12996125
Gene end: 13005383
  
Corresponding Affymetrix probe sets: 10407797 (MoGene1.0st)   1427760_s_at (Mouse Genome 430 2.0 Array)   1437515_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152202
Ensembl peptide - ENSMUSP00000152538
Ensembl peptide - ENSMUSP00000152254
Ensembl peptide - ENSMUSP00000106224
NCBI entrez gene - 18811     See in Manteia.
MGI - MGI:97618
RefSeq - NM_031191
RefSeq - XM_017315421
RefSeq Peptide - NP_112468
swissprot - A0A1Y7VLI3
swissprot - P04095
swissprot - A0A0M6L0W4
Ensembl - ENSMUSG00000079092
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prlENSDARG00000037946Danio rerio
 prlENSGALG00000012671Gallus gallus
 PRLENSG00000172179Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P04768 / Prl2c3 / Mus musculus prolactin family 2, subfamily c, member 4 (Prl2c4), mRNA. / PRL* / P01236* / prolactin*ENSMUSG0000005645799
Prl2c5 / Q9JLV9 / Prolactin-2C5 / PRL* / P01236* / prolactin*ENSMUSG0000005536087
Prl2c1 / Prolactin family 2, subfamily c, member 1 / PRL* / P01236* / prolactin*ENSMUSG0000006255185
Prl2a1 / Q9JHK0 / prolactin family 2, subfamily a, member 1 / PRL* / P01236* / prolactin*ENSMUSG0000002288643
Prl2b1 / Q9DAZ2 / prolactin family 2, subfamily b, member 1 / PRL* / P01236* / prolactin*ENSMUSG0000006925838
Prl6a1 / O35257 / prolactin family 6, subfamily a, member 1 / PRL* / P01236* / prolactin*ENSMUSG0000006925933
Prl7d1 / P04769 / prolactin family 7, subfamily d, member 1 / PRL* / P01236* / prolactin*ENSMUSG0000002134833
Prl3a1 / prolactin family 3, subfamily a, member 1 / PRL* / P01236* / prolactin*ENSMUSG0000003888333
Prl4a1 / O35256 / prolactin family 4, subfamily a, member 1 / PRL* / P01236* / prolactin*ENSMUSG0000000589132
Prl3b1 / P09586 / prolactin family 3, subfamily b, member 1 / PRL* / P01236* / prolactin*ENSMUSG0000003889131
Prl / P06879 / prolactin / P01236*ENSMUSG0000002134230
Prl7b1 / Q8CGZ9 / Prolactin-7B1 / PRL* / P01236* / prolactin*ENSMUSG0000002134730
Prl3d1 / prolactin family 3, subfamily d, member 1 / PRL* / P01236* / prolactin*ENSMUSG0000005717030
Prl3d2 / prolactin family 3, subfamily d, member 1 / PRL* / P01236* / prolactin*ENSMUSG0000006273729
Prl3d3 / prolactin family 3, subfamily d, member 3 / PRL* / P01236* / prolactin*ENSMUSG0000006220129
Prl7c1 / Q9CRB5 / prolactin family 7, subfamily c, member 1 / PRL* / P01236* / prolactin*ENSMUSG0000006073826
Prl5a1 / Q9JII2 / prolactin family 5, subfamily a, member 1 / PRL* / P01236* / prolactin*ENSMUSG0000001706426
Prl3c1 / Q9QUN5 / prolactin family 3, subfamily c, member 1 / PRL* / P01236* / prolactin*ENSMUSG0000001792224


Protein motifs (from Interpro)
Interpro ID Name
 IPR001400  Somatotropin/prolactin
 IPR009079  Four-helical cytokine-like, core
 IPR018116  Somatotropin hormone, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002040 sprouting angiogenesis IDA
 biological_processGO:0002052 positive regulation of neuroblast proliferation IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0031346 positive regulation of cell projection organization IDA
 biological_processGO:0032534 regulation of microvillus assembly IDA
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IDA
 biological_processGO:0045662 negative regulation of myoblast differentiation IDA
 biological_processGO:0045766 positive regulation of angiogenesis IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity IDA


Pathways (from Reactome)
Pathway description
Prolactin receptor signaling
Growth hormone receptor signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: E2f7tm1Gle/E2f7tm1Gle,E2f8tm1Gle/E2f8tm1Gle,Prl2c2tm1(cre)Gle/Prl2c2+
Genetic Background: involves: 129S6/SvEvTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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