ENSGALG00000012671


Gallus gallus

Features
Gene ID: ENSGALG00000012671
  
Biological name :prl
  
Synonyms : P14676 / prl / Prolactin
  
Possible biological names infered from orthology : Mus musculus prolactin family 2, subfamily c, member 4 (Prl2c4), mRNA. / O35256 / O35257 / P01236 / P04095 / P04768 / P04769 / P06879 / P09586 / Prl2a1 / Prl2b1 / Prl2c1 / Prl2c2 / Prl2c3 / Prl2c5 / Prl3a1 / Prl3b1 / Prl3c1 / Prl3d1 / Prl3d2 / Prl3d3 / Prl4a1 / Prl5a1 / Prl6a1 / Prl7b1 / Prl7c1 / Prl7d1 / Prolactin-2C2 / Prolactin-2C5 / Prolactin-7B1 / prolactin family 2, subfamily a, member 1 / prolactin family 2, subfamily b, member 1 / Prolactin family 2, subfamily c, member 1 / prolactin family 3, subfamily a, member 1 / prolactin family 3, subfamily b, member 1 / prolactin family 3, subfamily c, member 1 / prolactin family 3, subfamily d, member 1 / prolactin family 3, subfamily d, member 3 / prolactin family 4, subfamily a, member 1 / prolactin family 5, subfamily a, member 1 / prolactin family 6, subfamily a, member 1 / prolactin family 7, subfamily c, member 1 / prolactin family 7, subfamily d, member 1 / Q8CGZ9 / Q9CRB5 / Q9DAZ2 / Q9JHK0 / Q9JII2 / Q9JLV9 / Q9QUN5
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 58772953
Gene end: 58779107
  
Corresponding Affymetrix probe sets: GgaAffx.21806.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000020651
Ensembl peptide - ENSGALP00000062872
Ensembl peptide - ENSGALP00000058704
Ensembl peptide - ENSGALP00000053125
Ensembl peptide - ENSGALP00000044443
NCBI entrez gene - 396453     See in Manteia.
RefSeq - NM_205466
RefSeq Peptide - NP_990797
swissprot - A0A0B5L5F3
swissprot - A0A1D5PJX6
swissprot - P14676
swissprot - A0A0B5KZ08
swissprot - A0A0B5LBD4
Ensembl - ENSGALG00000012671
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prlENSDARG00000037946Danio rerio
 PRLENSG00000172179Homo sapiens
 O35256ENSMUSG00000005891Mus musculus
 O35257ENSMUSG00000069259Mus musculus
 P04095ENSMUSG00000079092Mus musculus
 P04768ENSMUSG00000056457Mus musculus
 P04769ENSMUSG00000021348Mus musculus
 P09586ENSMUSG00000038891Mus musculus
 PrlENSMUSG00000021342Mus musculus
 Prl2a1ENSMUSG00000022886Mus musculus
 Prl2b1ENSMUSG00000069258Mus musculus
 Prl2c1ENSMUSG00000062551Mus musculus
 Prl2c5ENSMUSG00000055360Mus musculus
 Prl3a1ENSMUSG00000038883Mus musculus
 Prl3c1ENSMUSG00000017922Mus musculus
 Prl3d1ENSMUSG00000057170Mus musculus
 Prl3d2ENSMUSG00000062737Mus musculus
 Prl3d3ENSMUSG00000062201Mus musculus
 Prl5a1ENSMUSG00000017064Mus musculus
 Prl7b1ENSMUSG00000021347Mus musculus
 Prl7c1ENSMUSG00000060738Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRLL / prolactin-like protein precursor ENSGALG0000000960328


Protein motifs (from Interpro)
Interpro ID Name
 IPR001400  Somatotropin/prolactin
 IPR009079  Four-helical cytokine-like, core
 IPR018116  Somatotropin hormone, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001937 negative regulation of endothelial cell proliferation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0033685 negative regulation of luteinizing hormone secretion TAS
 biological_processGO:0040014 regulation of multicellular organism growth IEA
 biological_processGO:0046427 positive regulation of JAK-STAT cascade IEA
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space TAS
 molecular_functionGO:0005179 hormone activity IEA


Pathways (from Reactome)
Pathway description
Prolactin receptor signaling
Growth hormone receptor signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000249 GH / P08998 / Somatotropin / GH2* / GH1* / CSH1* / CSH2* / CSHL1* / Q14406* / P0DML3* / P0DML2* / P01241* / P01242* / P06880* / growth hormone 1* / growth hormone 2* / chorionic somatomamm...  / complex
 ENSGALG00000006474 SKP1 / Q5ZKF5 / S-phase kinase-associated protein 1 / Skp1a* / Q9WTX5* / P63208* / AC104109.3* / S-phase kinase-associated protein 1A*  / complex / reaction
 ENSGALG00000015027 JAK2 / Janus kinase 2 / O60674*  / complex / reaction
 ENSGALG00000012671 prl / P14676 / Prolactin / P04095* / P04768* / P04769* / P06879* / P09586* / Prl2a1* / Prl2b1* / Prl2c1* / Prl2c2* / Prl2c3* / Prl2c5* / Prl3a1* / Prl3b1* / Prl3c1* / Prl3d1* / Prl3d2* / P...  / complex
 ENSGALG00000011993 RBX1 / ring-box 1 / P62877* / P62878* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / reaction / complex
 ENSGALG00000036941 CUL1 / cullin 1 / Q13616* / Q9WTX6* / Mus musculus cullin 1 (Cul1), transcript variant 3, mRNA.*  / complex / reaction






 

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