ENSDARG00000039434


Danio rerio

Features
Gene ID: ENSDARG00000039434
  
Biological name :oprm1
  
Synonyms : opioid receptor, mu 1 / oprm1
  
Possible biological names infered from orthology : P35372 / P42866
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 23843712
Gene end: 23882977
  
Corresponding Affymetrix probe sets: Dr.10726.1.S1_at (Zebrafish Array)   NM_131707_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000057610
NCBI entrez gene - 65088     See in Manteia.
RefSeq - NM_131707
RefSeq Peptide - NP_571782
swissprot - B8JHS2
ZFIN ID - ZDB-GENE-010125-1
Ensembl - ENSDARG00000039434
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OPRM1ENSGALG00000013616Gallus gallus
 OPRM1ENSG00000112038Homo sapiens
 Oprm1ENSMUSG00000000766Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
oprd1b / opioid receptor, delta 1b / OPRD1* / P32300* / P41143* / opioid receptor delta 1*ENSDARG0000003715961
oprd1a / opioid receptor, delta 1a / OPRD1* / P32300* / P41143* / opioid receptor delta 1*ENSDARG0000004166060
oprk1 / opioid receptor, kappa 1 / P33534* / P41145* / Kappa-type opioid receptor *ENSDARG0000000689455
oprl1 / opiate receptor-like 1 / P41146* / P35377* / opioid receptor-like 1* / opioid related nociceptin receptor 1*ENSDARG0000007120954
sstr1b / somatostatin receptor 1b / SSTR4* / P31391* / somatostatin receptor 4*ENSDARG0000006792535
sstr2a / somatostatin receptor 2a / SSTR2* / P30874* / somatostatin receptor 2*ENSDARG0000005909034
si:zfos-169g10.2 / SSTR3* / P32745* / P30935* / somatostatin receptor 3* / Somatostatin receptor type 3 *ENSDARG0000010366234
npbwr2a / neuropeptides B/W receptor 2a / NPBWR2* / P48146* / neuropeptides B and W receptor 2*ENSDARG0000007942333
sstr2b / somatostatin receptor 2b / SSTR2* / P30874* / somatostatin receptor 2*ENSDARG0000006980633
sstr1a / somatostatin receptor 1a / SSTR1* / P30872* / P30873* / somatostatin receptor 1*ENSDARG0000010492233
sstr3 / somatostatin receptor 3 / P30935* / P32745* / Somatostatin receptor type 3 *ENSDARG0000001447733
sstr5 / somatostatin receptor 5 / O08858* / P35346* / Somatostatin receptor type 5 *ENSDARG0000010165531
MCHR2 / si:dkey-165n16.5 / Q969V1* / melanin concentrating hormone receptor 2*ENSDARG0000000784224
mchr1b / melanin-concentrating hormone receptor 1b / MCHR1* / Q99705* / Q8JZL2* / melanin concentrating hormone receptor 1*ENSDARG0000002252524
mchr2 / melanin-concentrating hormone receptor 2ENSDARG0000003611724
mchr1a / melanin-concentrating hormone receptor 1a / MCHR1* / Q99705* / Q8JZL2* / melanin concentrating hormone receptor 1*ENSDARG0000010409323


Protein motifs (from Interpro)
Interpro ID Name
 IPR000105  Mu opioid receptor
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001418  Opioid receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IBA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0019233 sensory perception of pain IBA
 biological_processGO:0038003 opioid receptor signaling pathway IEA
 biological_processGO:0071315 cellular response to morphine IBA
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043005 neuron projection IBA
 molecular_functionGO:0001965 G-protein alpha-subunit binding IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004979 beta-endorphin receptor activity IBA
 molecular_functionGO:0004985 opioid receptor activity IEA
 molecular_functionGO:0031681 G-protein beta-subunit binding IBA
 molecular_functionGO:0038046 enkephalin receptor activity IDA
 molecular_functionGO:0038047 morphine receptor activity IBA
 molecular_functionGO:0042923 neuropeptide binding IBA


Pathways (from Reactome)
Pathway description
Opioid Signalling
G-protein activation
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain mitotic cell cycle increased process quality , abnormal
brain decreased amount , abnormal
Show

 ZFA:0000012 central nervous system central nervous system decreased amount , abnormal
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 ZFA:0000029 hindbrain hindbrain anterior-most region apoptotic , abnormal
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 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
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 ZFA:0000100 cerebellum cerebellum apoptotic , abnormal
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 ZFA:0000107 eye eye apoptotic , abnormal
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 ZFA:0000109 forebrain forebrain apoptotic , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle mitotic cell cycle increased process quality , abnormal
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 ZFA:0000445 optic tectum optic tectum mitotic cell cycle increased process quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000087798 pdyn / prodynorphin / P01213*  / reaction / complex
 ENSDARG00000056831 gng2 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / P63213* / G protein subunit gamma 2*  / complex / reaction
 ENSDARG00000043135 pomca / proopiomelanocortin a / POMC* / P01193* / P01189* / proopiomelanocortin* / pro-opiomelanocortin-alpha*  / complex / reaction
 ENSDARG00000104372 gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*  / complex / reaction
 ENSDARG00000069307 pomcb / proopiomelanocortin b / POMC* / P01193* / P01189* / proopiomelanocortin* / pro-opiomelanocortin-alpha*  / reaction / complex
 ENSDARG00000090454 gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*  / complex / reaction






 

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