ENSDARG00000040319


Danio rerio

Features
Gene ID: ENSDARG00000040319
  
Biological name :CABZ01041494.1
  
Synonyms : C5a anaphylatoxin chemotactic receptor 1 / CABZ01041494.1 / P0C7U5
  
Possible biological names infered from orthology : C5AR1 / C5AR2 / complement C5a receptor 1 / complement component 5a receptor 2 / P21730 / P30993 / Q9P296
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 46798159
Gene end: 46799199
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000059000
NCBI entrez gene - 100000959     See in Manteia.
swissprot - P0C7U5
Ensembl - ENSDARG00000040319
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 C5AR1ENSG00000197405Homo sapiens
 C5AR2ENSG00000134830Homo sapiens
 C5ar1ENSMUSG00000049130Mus musculus
 C5ar2ENSMUSG00000074361Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CU861476.1 / C3AR1* / Q16581* / complement C3a receptor 1*ENSDARG0000003174934
fpr1 / formyl peptide receptor 1 / GPR33* / Q49SQ1* / O88416* / Probable G-protein coupled receptor 33 * / G protein-coupled receptor 33 (gene/pseudogene)*ENSDARG0000004298434
si:dkey-42l23.2ENSDARG0000001108331
si:ch73-160i9.3 / si:ch211-171h4.6ENSDARG0000007657430
si:ch73-160i9.3ENSDARG0000005854730
si:ch73-160i9.1ENSDARG0000006311129
si:ch73-160i9.1 / si:ch73-160i9.2ENSDARG0000001909329
si:dkey-211g8.1ENSDARG0000003672829
gpr1 / G protein-coupled receptor 1 / P46091*ENSDARG0000010136628
si:dkey-42l23.4ENSDARG0000009778227
si:ch211-240b21.4 / si:ch211-240b21.5 / CMKLR1 (1 of many) / CMKLR1* / P97468* / Q99788* / chemerin chemokine-like receptor 1* / Mus musculus chemokine-like receptor 1 (Cmklr1), transcript ...ENSDARG0000010965427
CR848763.1ENSDARG0000009725027
cmklr1 / chemokine-like receptor 1 / P97468* / Q99788* / chemerin chemokine-like receptor 1* / Mus musculus chemokine-like receptor 1 (Cmklr1), transcript variant 1, mRNA.*ENSDARG0000009089027
si:dkey-42l23.7ENSDARG0000007671026
si:dkey-117a8.3ENSDARG0000005392826
si:dkey-117a8.1ENSDARG0000009781626
si:dkey-117a8.4ENSDARG0000009769826
si:dkey-42l23.5ENSDARG0000005393125
si:ch211-240b21.4 / CMKLR1 (1 of many) / Q99788* / CMKLR1* / P97468* / chemerin chemokine-like receptor 1* / Mus musculus chemokine-like receptor 1 (Cmklr1), transcript variant 1, mRNA.*ENSDARG0000011036225
si:ch211-137j23.6ENSDARG0000009787224


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000826  Formyl peptide receptor-related
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002430 complement receptor mediated signaling pathway IBA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IBA
 biological_processGO:0038178 complement component C5a signaling pathway IEA
 biological_processGO:0042789 mRNA transcription by RNA polymerase II ISS
 biological_processGO:0050679 positive regulation of epithelial cell proliferation ISS
 biological_processGO:0050900 leukocyte migration IBA
 biological_processGO:0060326 cell chemotaxis IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane ISS
 cellular_componentGO:0045177 apical part of cell ISS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004875 complement receptor activity IBA
 molecular_functionGO:0004878 complement component C5a receptor activity ISS
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events
Neutrophil degranulation
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000021004 c5 / complement component 5 / P01031* / complement C5*  / complex / reaction






 

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