ENSDARG00000044251


Danio rerio

Features
Gene ID: ENSDARG00000044251
  
Biological name :rasgef1bb
  
Synonyms : Q6DBW1 / rasgef1bb / RasGEF domain family, member 1Bb
  
Possible biological names infered from orthology : Q0VAM2 / Q8JZL7 / RASGEF1B / Ras-GEF domain-containing family member 1B / RasGEF domain family member 1B
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 9159279
Gene end: 9184667
  
Corresponding Affymetrix probe sets: Dr.13285.1.A1_at (Zebrafish Array)   NM_001003479_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000064967
NCBI entrez gene - 445085     See in Manteia.
RefSeq - NM_001003479
RefSeq Peptide - NP_001003479
swissprot - Q6DBW1
ZFIN ID - ZDB-GENE-040801-220
Ensembl - ENSDARG00000044251
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000010903Gallus gallus
 Q0VAM2ENSG00000138670Homo sapiens
 Q8JZL7ENSMUSG00000089809Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6DHR3 / rasgef1ba / RasGEF domain family, member 1Ba / Q8JZL7* / Q0VAM2* / RASGEF1B* / RasGEF domain family member 1B* / Ras-GEF domain-containing family member 1B *ENSDARG0000003361472
si:dkey-253i9.4ENSDARG0000006145924
rapgef2 / Rap guanine nucleotide exchange factor (GEF) 2 / Q8CHG7* / Q9Y4G8* / Rap guanine nucleotide exchange factor 2*ENSDARG0000000548224
rapgef6 / Rap guanine nucleotide exchange factor (GEF) 6 / Q8TEU7* / AC008695.1* / Rap guanine nucleotide exchange factor 6*ENSDARG0000001094523
rapgef4 / Rap guanine nucleotide exchange factor (GEF) 4 / Q8WZA2* / Q9EQZ6* / Rap guanine nucleotide exchange factor 4*ENSDARG0000007987220
zgc:171558 / Q8WZA2* / Q9EQZ6* / RAPGEF4* / Rap guanine nucleotide exchange factor 4* / Rap guanine nucleotide exchange factor (GEF) 4*ENSDARG0000007592420
rapgef3 / Rap guanine nucleotide exchange factor (GEF) 3 / Q8VCC8* / O95398* / Rap guanine nucleotide exchange factor 3* / Mus musculus Rap guanine nucleotide exchange factor (GEF) 3 (Rapge...ENSDARG0000007929119
rapgefl1 / Rap guanine nucleotide exchange factor (GEF)-like 1 / Q68EF8* / Q9UHV5* / Rap guanine nucleotide exchange factor like 1*ENSDARG0000007991217
rapgef5a / Rap guanine nucleotide exchange factor (GEF) 5a / Q92565* / RAPGEF5* / Rap guanine nucleotide exchange factor 5*ENSDARG0000007527117
rasgrp4 / RAS guanyl releasing protein 4 / Q8BTM9* / Q8TDF6*ENSDARG0000006179616
rasgrp3 / RAS guanyl releasing protein 3 (calcium and DAG-regulated) / Q8IV61* / RAS guanyl releasing protein 3*ENSDARG0000007786416
RASGRP2 / RAS guanyl releasing protein 2 / Q7LDG7*ENSDARG0000009909215
rasgrp2 / RAS guanyl releasing protein 2 (calcium and DAG-regulated) / Q7LDG7* / Q9QUG9* / RAS guanyl releasing protein 2*ENSDARG0000006232814


Protein motifs (from Interpro)
Interpro ID Name
 IPR000651  Ras-like guanine nucleotide exchange factor, N-terminal
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR019804  Ras guanine-nucleotide exchange factor, conserved site
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR030710  Ras-GEF domain-containing family member 1B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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