ENSG00000138670


Homo sapiens

Features
Gene ID: ENSG00000138670
  
Biological name :RASGEF1B
  
Synonyms : Q0VAM2 / RASGEF1B / RasGEF domain family member 1B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q21.22
Gene start: 81426393
Gene end: 82044244
  
Corresponding Affymetrix probe sets: 1553785_at (Human Genome U133 Plus 2.0 Array)   1554999_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000425393
Ensembl peptide - ENSP00000490814
Ensembl peptide - ENSP00000490436
Ensembl peptide - ENSP00000484927
Ensembl peptide - ENSP00000476065
Ensembl peptide - ENSP00000426929
Ensembl peptide - ENSP00000264400
Ensembl peptide - ENSP00000338437
Ensembl peptide - ENSP00000398763
NCBI entrez gene - 153020     See in Manteia.
OMIM - 614532
RefSeq - XM_017007813
RefSeq - NM_001300735
RefSeq - NM_001300736
RefSeq - NM_152545
RefSeq - XM_017007812
RefSeq Peptide - NP_001287665
RefSeq Peptide - NP_689758
RefSeq Peptide - NP_001287664
swissprot - A0A0G2JLL4
swissprot - A0A1B0GW78
swissprot - Q8N437
swissprot - Q0VAM2
swissprot - D6RE71
swissprot - A0A1B0GVA7
Ensembl - ENSG00000138670
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6DBW1ENSDARG00000044251Danio rerio
 Q6DHR3ENSDARG00000033614Danio rerio
 ENSGALG00000010903Gallus gallus
 Q8JZL7ENSMUSG00000089809Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8N431 / RASGEF1C / RasGEF domain family member 1CENSG0000014609068
Q8N9B8 / RASGEF1A / RasGEF domain family member 1AENSG0000019891560
Q9Y4G8 / RAPGEF2 / Rap guanine nucleotide exchange factor 2ENSG0000010975625
AC008695.1ENSG0000027321723
Q8TEU7 / RAPGEF6 / Rap guanine nucleotide exchange factor 6ENSG0000015898723
Q92565 / RAPGEF5 / Rap guanine nucleotide exchange factor 5ENSG0000013623720
O95398 / RAPGEF3 / Rap guanine nucleotide exchange factor 3ENSG0000007933720
O95267 / RASGRP1 / RAS guanyl releasing protein 1ENSG0000017257520
Q8WZA2 / RAPGEF4 / Rap guanine nucleotide exchange factor 4ENSG0000009142819
Q8IV61 / RASGRP3 / RAS guanyl releasing protein 3ENSG0000015268917
Q8TDF6 / RASGRP4 / RAS guanyl releasing protein 4ENSG0000017177716
Q9UHV5 / RAPGEFL1 / Rap guanine nucleotide exchange factor like 1ENSG0000010835216
Q7LDG7 / RASGRP2 / RAS guanyl releasing protein 2ENSG0000006883116


Protein motifs (from Interpro)
Interpro ID Name
 IPR000651  Ras-like guanine nucleotide exchange factor, N-terminal
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR019804  Ras guanine-nucleotide exchange factor, conserved site
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR030710  Ras-GEF domain-containing family member 1B
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0030496 midbody IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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