ENSG00000108352


Homo sapiens

Features
Gene ID: ENSG00000108352
  
Biological name :RAPGEFL1
  
Synonyms : Q9UHV5 / RAPGEFL1 / Rap guanine nucleotide exchange factor like 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q21.1
Gene start: 40177010
Gene end: 40195656
  
Corresponding Affymetrix probe sets: 218657_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000444646
Ensembl peptide - ENSP00000479735
Ensembl peptide - ENSP00000264644
Ensembl peptide - ENSP00000394530
Ensembl peptide - ENSP00000438631
Ensembl peptide - ENSP00000440006
Ensembl peptide - ENSP00000440226
Ensembl peptide - ENSP00000441059
NCBI entrez gene - 51195     See in Manteia.
RefSeq - XM_006721938
RefSeq - NM_001303533
RefSeq - NM_001303534
RefSeq - NM_016339
RefSeq - XM_006721932
RefSeq - XM_006721935
RefSeq - XM_006721937
RefSeq Peptide - NP_001290463
RefSeq Peptide - NP_001290462
RefSeq Peptide - NP_057423
swissprot - Q9UHV5
swissprot - F5GYJ3
swissprot - F5H2D5
swissprot - F5H582
swissprot - F5GY17
swissprot - A0A087WVW6
swissprot - F5GXC6
Ensembl - ENSG00000108352
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rapgefl1ENSDARG00000079912Danio rerio
 RAPGEFL1ENSGALG00000035690Gallus gallus
 Q68EF8ENSMUSG00000038020Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8WZA2 / RAPGEF4 / Rap guanine nucleotide exchange factor 4ENSG0000009142839
Q92565 / RAPGEF5 / Rap guanine nucleotide exchange factor 5ENSG0000013623739
O95398 / RAPGEF3 / Rap guanine nucleotide exchange factor 3ENSG0000007933733
Q9Y4G8 / RAPGEF2 / Rap guanine nucleotide exchange factor 2ENSG0000010975624
Q8TEU7 / RAPGEF6 / Rap guanine nucleotide exchange factor 6ENSG0000015898722
AC008695.1ENSG0000027321722
Q8N431 / RASGEF1C / RasGEF domain family member 1CENSG0000014609016
Q8TDF6 / RASGRP4 / RAS guanyl releasing protein 4ENSG0000017177715
Q0VAM2 / RASGEF1B / RasGEF domain family member 1BENSG0000013867015
Q8IV61 / RASGRP3 / RAS guanyl releasing protein 3ENSG0000015268915
O95267 / RASGRP1 / RAS guanyl releasing protein 1ENSG0000017257514
Q8N9B8 / RASGEF1A / RasGEF domain family member 1AENSG0000019891514
Q7LDG7 / RASGRP2 / RAS guanyl releasing protein 2ENSG0000006883112


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR003116  Raf-like Ras-binding
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR029071  Ubiquitin-like domain superfamily
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0016020 membrane TAS
 molecular_functionGO:0005057 obsolete signal transducer activity, downstream of receptor IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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