ENSG00000273217


Homo sapiens

Features
Gene ID: ENSG00000273217
  
Biological name :AC008695.1
  
Synonyms : AC008695.1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q31.1
Gene start: 131425891
Gene end: 131796983
  
Corresponding Affymetrix probe sets: 1555247_a_at (Human Genome U133 Plus 2.0 Array)   219112_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000426948
swissprot - E9PCH4
Ensembl - ENSG00000273217
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rapgef6ENSDARG00000010945Danio rerio
 ENSGALG00000029896Gallus gallus
 Rapgef6ENSMUSG00000037533Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8TEU7 / RAPGEF6 / Rap guanine nucleotide exchange factor 6ENSG0000015898796
Q9Y4G8 / RAPGEF2 / Rap guanine nucleotide exchange factor 2ENSG0000010975657
Q8WZA2 / RAPGEF4 / Rap guanine nucleotide exchange factor 4ENSG0000009142814
O95398 / RAPGEF3 / Rap guanine nucleotide exchange factor 3ENSG0000007933713
Q92565 / RAPGEF5 / Rap guanine nucleotide exchange factor 5ENSG0000013623711
O95267 / RASGRP1 / RAS guanyl releasing protein 1ENSG000001725759
Q8N9B8 / RASGEF1A / RasGEF domain family member 1AENSG000001989157
Q8IV61 / RASGRP3 / RAS guanyl releasing protein 3ENSG000001526897
Q8TDF6 / RASGRP4 / RAS guanyl releasing protein 4ENSG000001717777
Q9UHV5 / RAPGEFL1 / Rap guanine nucleotide exchange factor like 1ENSG000001083527
Q0VAM2 / RASGEF1B / RasGEF domain family member 1BENSG000001386707
Q8N431 / RASGEF1C / RasGEF domain family member 1CENSG000001460906
Q7LDG7 / RASGRP2 / RAS guanyl releasing protein 2ENSG000000688316


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR000595  Cyclic nucleotide-binding domain
 IPR000651  Ras-like guanine nucleotide exchange factor, N-terminal
 IPR001478  PDZ domain
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR014710  RmlC-like jelly roll fold
 IPR018490  Cyclic nucleotide-binding-like
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR028084  Folliculin-interacting protein, N-terminal domain
 IPR036034  PDZ superfamily
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr