ENSMUSG00000089809


Mus musculus

Features
Gene ID: ENSMUSG00000089809
  
Biological name :Rasgef1b
  
Synonyms : Q8JZL7 / Rasgef1b / Ras-GEF domain-containing family member 1B
  
Possible biological names infered from orthology : Q0VAM2 / RasGEF domain family member 1B
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: E4
Gene start: 99217426
Gene end: 99729065
  
Corresponding Affymetrix probe sets: 10531610 (MoGene1.0st)   10531627 (MoGene1.0st)   1454742_at (Mouse Genome 430 2.0 Array)   1459349_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125057
Ensembl peptide - ENSMUSP00000147997
Ensembl peptide - ENSMUSP00000129652
Ensembl peptide - ENSMUSP00000128947
Ensembl peptide - ENSMUSP00000125723
Ensembl peptide - ENSMUSP00000031276
Ensembl peptide - ENSMUSP00000125009
NCBI entrez gene - 320292     See in Manteia.
MGI - MGI:2443755
RefSeq - NM_145839
RefSeq - NM_181318
RefSeq Peptide - NP_665838
RefSeq Peptide - NP_851835
swissprot - Q8JZL7
swissprot - E0CXU2
swissprot - E0CXS0
swissprot - A0A1B0GSM5
swissprot - E9Q813
Ensembl - ENSMUSG00000089809
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6DBW1ENSDARG00000044251Danio rerio
 Q6DHR3ENSDARG00000033614Danio rerio
 ENSGALG00000010903Gallus gallus
 Q0VAM2ENSG00000138670Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9D300 / Rasgef1c / Ras-GEF domain-containing family member 1C / Q8N431* / RasGEF domain family member 1C*ENSMUSG0000002037466
Rasgef1a / RasGEF domain family, member 1A / Q8N9B8*ENSMUSG0000003013460
Q8CHG7 / Rapgef2 / Rap guanine nucleotide exchange factor 2 / Q9Y4G8*ENSMUSG0000006223226
Rapgef6 / Rap guanine nucleotide exchange factor (GEF) 6 / Q8TEU7* / AC008695.1* / Rap guanine nucleotide exchange factor 6*ENSMUSG0000003753325
Q9EQZ6 / Rapgef4 / Rap guanine nucleotide exchange factor (GEF) 4 / Q8WZA2* / Rap guanine nucleotide exchange factor 4*ENSMUSG0000004904420
Q8VCC8 / Rapgef3 / Mus musculus Rap guanine nucleotide exchange factor (GEF) 3 (Rapgef3), transcript variant 4, mRNA. / O95398* / Rap guanine nucleotide exchange factor 3*ENSMUSG0000002246920
Q8C0Q9 / Rapgef5 / Rap guanine nucleotide exchange factor 5 / Q92565*ENSMUSG0000004199220
Q9Z1S3 / Rasgrp1 / RAS guanyl releasing protein 1 / O95267*ENSMUSG0000002734719
Rasgrp3 / RAS, guanyl releasing protein 3 / Q8IV61*ENSMUSG0000007104217
Q9QUG9 / Rasgrp2 / RAS, guanyl releasing protein 2 / Q7LDG7*ENSMUSG0000003294616
Q8BTM9 / Rasgrp4 / RAS guanyl releasing protein 4 / Q8TDF6*ENSMUSG0000003058916
Q68EF8 / Rapgefl1 / Rap guanine nucleotide exchange factor-like 1 / Q9UHV5*ENSMUSG0000003802016


Protein motifs (from Interpro)
Interpro ID Name
 IPR000651  Ras-like guanine nucleotide exchange factor, N-terminal
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR019804  Ras guanine-nucleotide exchange factor, conserved site
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR030710  Ras-GEF domain-containing family member 1B
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0030496 midbody IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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