ENSMUSG00000041992


Mus musculus

Features
Gene ID: ENSMUSG00000041992
  
Biological name :Rapgef5
  
Synonyms : Q8C0Q9 / Rapgef5 / Rap guanine nucleotide exchange factor 5
  
Possible biological names infered from orthology : Q92565
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: F2
Gene start: 117516479
Gene end: 117759737
  
Corresponding Affymetrix probe sets: 10399148 (MoGene1.0st)   1445255_at (Mouse Genome 430 2.0 Array)   1455137_at (Mouse Genome 430 2.0 Array)   1455840_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152479
Ensembl peptide - ENSMUSP00000152875
Ensembl peptide - ENSMUSP00000105313
Ensembl peptide - ENSMUSP00000152339
NCBI entrez gene - 217944     See in Manteia.
MGI - MGI:2444365
RefSeq - NM_175930
RefSeq - XM_006515781
RefSeq Peptide - NP_787126
swissprot - A0A1Y7VJI0
swissprot - Q8C0Q9
Ensembl - ENSMUSG00000041992
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rapgef5aENSDARG00000075271Danio rerio
 RAPGEF5ENSGALG00000034024Gallus gallus
 Q92565ENSG00000136237Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9EQZ6 / Rapgef4 / Rap guanine nucleotide exchange factor (GEF) 4 / Q8WZA2* / Rap guanine nucleotide exchange factor 4*ENSMUSG0000004904441
Q8VCC8 / Rapgef3 / Mus musculus Rap guanine nucleotide exchange factor (GEF) 3 (Rapgef3), transcript variant 4, mRNA. / O95398* / Rap guanine nucleotide exchange factor 3*ENSMUSG0000002246935
Q68EF8 / Rapgefl1 / Rap guanine nucleotide exchange factor-like 1 / Q9UHV5*ENSMUSG0000003802028
Q8CHG7 / Rapgef2 / Rap guanine nucleotide exchange factor 2 / Q9Y4G8*ENSMUSG0000006223223
Rapgef6 / Rap guanine nucleotide exchange factor (GEF) 6 / Q8TEU7* / AC008695.1* / Rap guanine nucleotide exchange factor 6*ENSMUSG0000003753323
Rasgef1a / RasGEF domain family, member 1A / Q8N9B8*ENSMUSG0000003013413
Q8JZL7 / Rasgef1b / Ras-GEF domain-containing family member 1B / Q0VAM2* / RasGEF domain family member 1B*ENSMUSG0000008980912
Q9D300 / Rasgef1c / Ras-GEF domain-containing family member 1C / Q8N431* / RasGEF domain family member 1C*ENSMUSG0000002037411
Rasgrp3 / RAS, guanyl releasing protein 3 / Q8IV61*ENSMUSG0000007104210
Q8BTM9 / Rasgrp4 / RAS guanyl releasing protein 4 / Q8TDF6*ENSMUSG0000003058910
Q9Z1S3 / Rasgrp1 / RAS guanyl releasing protein 1 / O95267*ENSMUSG0000002734710
Q9QUG9 / Rasgrp2 / RAS, guanyl releasing protein 2 / Q7LDG7*ENSMUSG000000329469


Protein motifs (from Interpro)
Interpro ID Name
 IPR000591  DEP domain
 IPR000651  Ras-like guanine nucleotide exchange factor, N-terminal
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR019804  Ras guanine-nucleotide exchange factor, conserved site
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR029071  Ubiquitin-like domain superfamily
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0016604 nuclear body ISO
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0017034 Rap guanyl-nucleotide exchange factor activity ISS
 molecular_functionGO:0030742 GTP-dependent protein binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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