ENSDARG00000045557


Danio rerio

Features
Gene ID: ENSDARG00000045557
  
Biological name :socs2
  
Synonyms : socs2 / suppressor of cytokine signaling 2
  
Possible biological names infered from orthology : O14508 / O35717
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 18432182
Gene end: 18436899
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000152969
Ensembl peptide - ENSDARP00000114987
NCBI entrez gene - 562062     See in Manteia.
RefSeq - NM_001114550
RefSeq Peptide - NP_001108022
swissprot - B0EVP5
ZFIN ID - ZDB-GENE-041210-171
Ensembl - ENSDARG00000045557
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SOCS2ENSGALG00000011295Gallus gallus
 SOCS2ENSG00000120833Homo sapiens
 Socs2ENSMUSG00000020027Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cishb / cytokine inducible SH2-containing protein b / CISH* / Q62225* / Q9NSE2* / cytokine inducible SH2 containing protein*ENSDARG0000001677339
cish / cytokine inducible SH2-containing protein / Q62225* / Q9NSE2*ENSDARG0000006031636
socs6a / suppressor of cytokine signaling 6a / SOCS6* / O14544* / suppressor of cytokine signaling 6*ENSDARG0000005856530
socs6b / suppressor of cytokine signaling 6bENSDARG0000001586329
socs1a / suppressor of cytokine signaling 1a / SOCS1* / O35716* / O15524* / suppressor of cytokine signaling 1*ENSDARG0000003809528
socs3b / suppressor of cytokine signaling 3b / SOCS3* / O35718* / O14543* / suppressor of cytokine signaling 3*ENSDARG0000002661128
socs5b / suppressor of cytokine signaling 5b / SOCS5* / O75159* / O54928* / suppressor of cytokine signaling 5*ENSDARG0000006274527
socs3a / suppressor of cytokine signaling 3a / SOCS3* / O14543* / suppressor of cytokine signaling 3*ENSDARG0000002542827
socs4 / suppressor of cytokine signaling 4ENSDARG0000007850926
socs7 / suppressor of cytokine signaling 7 / O14512*ENSDARG0000007701826
socs5a / suppressor of cytokine signaling 5a / SOCS5* / O75159* / O54928* / suppressor of cytokine signaling 5*ENSDARG0000010071726
socs9 / suppressor of cytokine signaling 9ENSDARG0000010198526
socs1b / suppressor of cytokine signaling 1bENSDARG0000008987322


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001496  SOCS box domain
 IPR028410  Suppressor of cytokine signalling 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IEA
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005159 insulin-like growth factor receptor binding IEA
 molecular_functionGO:0008269 JAK pathway signal transduction adaptor activity IEA


Pathways (from Reactome)
Pathway description
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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