ENSDARG00000016773


Danio rerio

Features
Gene ID: ENSDARG00000016773
  
Biological name :cishb
  
Synonyms : cishb / cytokine inducible SH2-containing protein b
  
Possible biological names infered from orthology : CISH / cytokine inducible SH2 containing protein / Q62225 / Q9NSE2
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 17959507
Gene end: 17964525
  
Corresponding Affymetrix probe sets: Dr.16100.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000017764
NCBI entrez gene - 100136861     See in Manteia.
RefSeq - NM_001114554
RefSeq - XM_017358181
RefSeq Peptide - NP_001108026
swissprot - L0N8L8
ZFIN ID - ZDB-GENE-080204-120
Ensembl - ENSDARG00000016773
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CISHENSGALG00000002260Gallus gallus
 CISHENSG00000114737Homo sapiens
 CishENSMUSG00000032578Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cish / cytokine inducible SH2-containing protein / Q62225* / Q9NSE2*ENSDARG0000006031648
socs2 / suppressor of cytokine signaling 2 / O14508* / O35717*ENSDARG0000004555736
socs3b / suppressor of cytokine signaling 3b / SOCS3* / O35718* / O14543* / suppressor of cytokine signaling 3*ENSDARG0000002661129
socs3a / suppressor of cytokine signaling 3a / SOCS3* / O14543* / suppressor of cytokine signaling 3*ENSDARG0000002542828
socs5b / suppressor of cytokine signaling 5b / SOCS5* / O75159* / O54928* / suppressor of cytokine signaling 5*ENSDARG0000006274527
socs5a / suppressor of cytokine signaling 5a / SOCS5* / O75159* / O54928* / suppressor of cytokine signaling 5*ENSDARG0000010071726
socs1a / suppressor of cytokine signaling 1a / SOCS1* / O35716* / O15524* / suppressor of cytokine signaling 1*ENSDARG0000003809526
socs4 / suppressor of cytokine signaling 4ENSDARG0000007850926
socs7 / suppressor of cytokine signaling 7 / O14512*ENSDARG0000007701825
socs6b / suppressor of cytokine signaling 6bENSDARG0000001586325
socs6a / suppressor of cytokine signaling 6a / SOCS6* / O14544* / suppressor of cytokine signaling 6*ENSDARG0000005856525
socs1b / suppressor of cytokine signaling 1bENSDARG0000008987324
socs9 / suppressor of cytokine signaling 9ENSDARG0000010198523


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001496  SOCS box domain
 IPR028425  Cytokine-inducible SH2-containing protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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