ENSDARG00000051756


Danio rerio

Features
Gene ID: ENSDARG00000051756
  
Biological name :pdhx
  
Synonyms : pdhx / pyruvate dehydrogenase complex, component X
  
Possible biological names infered from orthology : O00330 / Pyruvate dehydrogenase protein X component, mitochondrial / Q8BKZ9
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 37428187
Gene end: 37435076
  
Corresponding Affymetrix probe sets: Dr.14026.1.A1_at (Zebrafish Array)   NM_200560_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000093629
Ensembl peptide - ENSDARP00000124646
NCBI entrez gene - 393532     See in Manteia.
RefSeq - NM_200560
RefSeq - XM_005170734
RefSeq Peptide - NP_956854
swissprot - Q6NW45
swissprot - F1R0J8
ZFIN ID - ZDB-GENE-040426-1539
Ensembl - ENSDARG00000051756
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PDHXENSGALG00000033753Gallus gallus
 PDHXENSG00000110435Homo sapiens
 PdhxENSMUSG00000010914Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dlat / dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) / P10515* / Q8BMF4* / dihydrolipoamide S-acetyltransferase* / Dihydrolipoyllysine-residue acetyl...ENSDARG0000001591837


Protein motifs (from Interpro)
Interpro ID Name
 IPR000089  Biotin/lipoyl attachment
 IPR001078  2-oxoacid dehydrogenase acyltransferase, catalytic domain
 IPR003016  2-oxo acid dehydrogenase, lipoyl-binding site
 IPR004167  Peripheral subunit-binding domain
 IPR011053  Single hybrid motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA


Pathways (from Reactome)
Pathway description
Regulation of pyruvate dehydrogenase (PDH) complex
Glyoxylate metabolism and glycine degradation
Signaling by Retinoic Acid
Pyruvate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000020876 pdk2a / pyruvate dehydrogenase kinase, isozyme 2a / PDK2* / Q9JK42* / Q15119* / pyruvate dehydrogenase kinase 2* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial *  / reaction
 ENSDARG00000013128 pdk1 / pyruvate dehydrogenase kinase, isozyme 1 / Q15118* / Q8BFP9* / pyruvate dehydrogenase kinase 1* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial *  / reaction
 ENSDARG00000054848 pdk4 / pyruvate dehydrogenase kinase, isozyme 4 / O70571* / Q16654* / pyruvate dehydrogenase kinase 4* / pyruvate dehydrogenase kinase, isoenzyme 4*  / reaction
 ENSDARG00000021346 pdhb / pyruvate dehydrogenase E1 beta subunit / P11177* / Q9D051* / Pyruvate dehydrogenase E1 component subunit beta, mitochondrial *  / complex
 ENSDARG00000015918 dlat / dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) / P10515* / Q8BMF4* / dihydrolipoamide S-acetyltransferase* / Dihydrolipoyllysine-residue acetyl...  / complex
 ENSDARG00000051756 pdhx / pyruvate dehydrogenase complex, component X / O00330* / Q8BKZ9* / Pyruvate dehydrogenase protein X component, mitochondrial *  / complex
 ENSDARG00000105187 gcshb / glycine cleavage system protein H (aminomethyl carrier), b / GCSH* / P23434* / Q91WK5* / AC092718.3* / AC092718.8* / glycine cleavage system protein H* / Glycine cleavage system H p...  / reaction
 ENSDARG00000008785 dldh / dihydrolipoamide dehydrogenase / DLD* / O08749* / P09622* / Dihydrolipoyl dehydrogenase, mitochondrial *  / complex
 ENSDARG00000099791 pdk3b / pyruvate dehydrogenase kinase, isozyme 3b / PDK3* / Q922H2* / Q15120* / pyruvate dehydrogenase kinase 3* / pyruvate dehydrogenase kinase, isoenzyme 3*  / reaction






 

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