ENSDARG00000051876


Danio rerio

Features
Gene ID: ENSDARG00000051876
  
Biological name :ush1c
  
Synonyms : ush1c / Usher syndrome 1C
  
Possible biological names infered from orthology : Q9Y6N9 / USH1 protein network component harmonin
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 22643954
Gene end: 22704233
  
Corresponding Affymetrix probe sets: Dr.22228.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000114530
Ensembl peptide - ENSDARP00000151717
Ensembl peptide - ENSDARP00000104456
Ensembl peptide - ENSDARP00000104974
NCBI entrez gene - 564412     See in Manteia.
RefSeq - NM_001039929
RefSeq Peptide - NP_001035018
swissprot - E7EZG9
swissprot - F1QEB2
swissprot - Q29RC0
ZFIN ID - ZDB-GENE-060312-41
Ensembl - ENSDARG00000051876
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 USH1CENSGALG00000006192Gallus gallus
 USH1CENSG00000006611Homo sapiens
 Ush1cENSMUSG00000030838Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
whrna / whirlin aENSDARG0000007536227
whrnb / whirlin b / WHRN* / Q80VW5* / Q9P202* / whirlin*ENSDARG0000006816625
pdzd7a / PDZ domain containing 7a / PDZD7* / Q9H5P4* / PDZ domain containing 7*ENSDARG0000007697420
pdzd11 / Q6NXB2 / PDZ domain containing 11 / Q9CZG9* / Q5EBL8* / PDZ domain-containing protein 11 *ENSDARG000000531947


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR030237  Harmonin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001964 startle response IMP
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0046549 retinal cone cell development IMP
 biological_processGO:0050808 synapse organization IMP
 biological_processGO:0060122 inner ear receptor cell stereocilium organization IMP
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000168 anterior macula anterior macula stereocilium bundle bent , abnormal
anterior macula stereocilium bundle splayed , abnormal
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 ZFA:0000281 hair cell posterior macula hair cell posterior macula decreased amount , abnormal
Show

 ZFA:0000678 hair cell anterior macula hair cell anterior macula decreased amount , abnormal
hair cell anterior macula stereocilium decreased amount , abnormal
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 ZFA:0001330 retinal outer plexiform layer retinal outer plexiform layer synapse disorganized , abnormal
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 ZFA:0009121 auditory receptor cell auditory receptor cell stereocilium bundle splayed , abnormal
auditory receptor cell kinocilium bent , abnormal
auditory receptor cell kinocilium absent , abnormal
Show

 ZFA:0009262 retinal cone cell retinal cone cell cytoskeleton of presynaptic active zone detached from retinal outer plexiform layer postsynaptic density, abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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