ENSDARG00000052782


Danio rerio

Features
Gene ID: ENSDARG00000052782
  
Biological name :glrba
  
Synonyms : glrba / glycine receptor, beta a
  
Possible biological names infered from orthology : GLRB / glycine receptor beta / Glycine receptor subunit beta / P48167 / P48168
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 21423010
Gene end: 21483832
  
Corresponding Affymetrix probe sets: Dr.7438.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000093565
NCBI entrez gene - 83412     See in Manteia.
RefSeq - XM_017355860
RefSeq - NM_131781
RefSeq Peptide - NP_571856
swissprot - Q9DES8
ZFIN ID - ZDB-GENE-010410-2
Ensembl - ENSDARG00000052782
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GLRBENSGALG00000009395Gallus gallus
 GLRBENSG00000109738Homo sapiens
 GlrbENSMUSG00000028020Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
glrbb / glycine receptor, beta b / GLRB* / P48167* / P48168* / glycine receptor beta* / Glycine receptor subunit beta *ENSDARG0000005276985
glra4a / glycine receptor, alpha 4a / GLRA4* / Q5JXX5* / Q61603* / glycine receptor alpha 4* / Glycine receptor subunit alpha-4 *ENSDARG0000000686542
glra4b / glycine receptor, alpha 4b / GLRA4* / Q5JXX5* / Q61603* / glycine receptor alpha 4* / Glycine receptor subunit alpha-4 *ENSDARG0000005810341
glra3 / glycine receptor, alpha 3ENSDARG0000001106641
glra2 / si:ch211-12n8.3ENSDARG0000007501241
glra1 / O93430 / glycine receptor, alpha 1 / Q64018* / P23415* / Glycine receptor subunit alpha-1 *ENSDARG0000001201940
gabrb1 / gamma-aminobutyric acid (GABA) A receptor, beta 1 / P18505* / P50571* / Gamma-aminobutyric acid receptor subunit beta-1 * / gamma-aminobutyric acid type A receptor beta1 subunit*ENSDARG0000007612730
gabrb4 / gamma-aminobutyric acid (GABA) A receptor, beta 4 / GABRQ* / Q9UN88* / Q9JLF1* / Gamma-aminobutyric acid receptor subunit theta * / gamma-aminobutyric acid type A receptor theta subunit*ENSDARG0000009909628
gabrb3 / gamma-aminobutyric acid (GABA) A receptor, beta 3ENSDARG0000002377127
GABRB2 (1 of many) / gamma-aminobutyric acid type A receptor beta2 subunit / GABRB2* / P47870*ENSDARG0000010003227
gabrr2b / gamma-aminobutyric acid (GABA) A receptor, rho 2b / P56476* / GABRR2* / P28476* / Gamma-aminobutyric acid receptor subunit rho-2 * / gamma-aminobutyric acid type A receptor rho2 subunit*ENSDARG0000001405727
FO704905.1 / GABRR1* / P24046* / gamma-aminobutyric acid type A receptor rho1 subunit*ENSDARG0000009808126
gabrp / gamma-aminobutyric acid (GABA) A receptor, piENSDARG0000002090126
gabrr3b / gamma-aminobutyric acid (GABA) A receptor, rho 3b / A8MPY1* / GABRR3* / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene)*ENSDARG0000003075026
gabrr3a / gamma-aminobutyric acid (GABA) A receptor, rho 3a / A8MPY1* / GABRR3* / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene)*ENSDARG0000002715326
gabrd / gamma-aminobutyric acid (GABA) A receptor, delta / O14764* / P22933* / Gamma-aminobutyric acid receptor subunit delta * / gamma-aminobutyric acid type A receptor delta subunit*ENSDARG0000005976325
gabrr1 / gamma-aminobutyric acid (GABA) A receptor, rho 1 / P24046* / P56475* / Gamma-aminobutyric acid receptor subunit rho-1 * / gamma-aminobutyric acid type A receptor rho1 subunit*ENSDARG0000004390225
AL929217.1 / GABRP* / O00591* / gamma-aminobutyric acid type A receptor pi subunit*ENSDARG0000005989125
gabrz / gamma-aminobutyric acid (GABA) A receptor, zetaENSDARG0000009451224
gabrr2b / gabrr2a / gamma-aminobutyric acid (GABA) A receptor, rho 2a / GABRR2* / P28476* / P56476* / Gamma-aminobutyric acid receptor subunit rho-2 * / gamma-aminobutyric acid type A recep...ENSDARG0000005298223


Protein motifs (from Interpro)
Interpro ID Name
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR008060  Glycine receptor beta
 IPR018000  Neurotransmitter-gated ion-channel, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0007218 neuropeptide signaling pathway IBA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0043200 response to amino acid IBA
 biological_processGO:0060012 synaptic transmission, glycinergic IBA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0016594 glycine binding IBA
 molecular_functionGO:0016934 extracellularly glycine-gated chloride channel activity IBA


Pathways (from Reactome)
Pathway description
Neurotransmitter receptors and postsynaptic signal transmission


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000012019 glra1 / O93430 / glycine receptor, alpha 1 / Q64018* / P23415* / Glycine receptor subunit alpha-1 *  / complex






 

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