ENSDARG00000058103


Danio rerio

Features
Gene ID: ENSDARG00000058103
  
Biological name :glra4b
  
Synonyms : glra4b / glycine receptor, alpha 4b
  
Possible biological names infered from orthology : GLRA4 / glycine receptor alpha 4 / Glycine receptor subunit alpha-4 / Q5JXX5 / Q61603
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 22515347
Gene end: 22544151
  
Corresponding Affymetrix probe sets: Dr.12385.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000026925
NCBI entrez gene - 192125     See in Manteia.
RefSeq - NM_001202511
RefSeq Peptide - NP_001189440
swissprot - F1QTT1
ZFIN ID - ZDB-GENE-020402-2
Ensembl - ENSDARG00000058103
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GLRA4ENSGALG00000004936Gallus gallus
 GLRA4ENSG00000188828Homo sapiens
 Glra4ENSMUSG00000018595Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
glra4a / glycine receptor, alpha 4a / GLRA4* / Q5JXX5* / Q61603* / glycine receptor alpha 4* / Glycine receptor subunit alpha-4 *ENSDARG0000000686567
glra2 / si:ch211-12n8.3ENSDARG0000007501262
glra3 / glycine receptor, alpha 3ENSDARG0000001106661
glra1 / O93430 / glycine receptor, alpha 1 / Q64018* / P23415* / Glycine receptor subunit alpha-1 *ENSDARG0000001201959
glrbb / glycine receptor, beta b / GLRB* / P48167* / P48168* / glycine receptor beta* / Glycine receptor subunit beta *ENSDARG0000005276940
glrba / glycine receptor, beta a / GLRB* / P48167* / P48168* / glycine receptor beta* / Glycine receptor subunit beta *ENSDARG0000005278238
gabrb4 / gamma-aminobutyric acid (GABA) A receptor, beta 4 / GABRQ* / Q9UN88* / Q9JLF1* / Gamma-aminobutyric acid receptor subunit theta * / gamma-aminobutyric acid type A receptor theta subunit*ENSDARG0000009909630
gabrb1 / gamma-aminobutyric acid (GABA) A receptor, beta 1 / P18505* / P50571* / Gamma-aminobutyric acid receptor subunit beta-1 * / gamma-aminobutyric acid type A receptor beta1 subunit*ENSDARG0000007612729
GABRB2 (1 of many) / gamma-aminobutyric acid type A receptor beta2 subunit / GABRB2* / P47870*ENSDARG0000010003228
gabrb3 / gamma-aminobutyric acid (GABA) A receptor, beta 3ENSDARG0000002377128
gabrd / gamma-aminobutyric acid (GABA) A receptor, delta / O14764* / P22933* / Gamma-aminobutyric acid receptor subunit delta * / gamma-aminobutyric acid type A receptor delta subunit*ENSDARG0000005976328
gabrr2b / gamma-aminobutyric acid (GABA) A receptor, rho 2b / P56476* / GABRR2* / P28476* / Gamma-aminobutyric acid receptor subunit rho-2 * / gamma-aminobutyric acid type A receptor rho2 subunit*ENSDARG0000001405727
gabrp / gamma-aminobutyric acid (GABA) A receptor, piENSDARG0000002090127
FO704905.1 / GABRR1* / P24046* / gamma-aminobutyric acid type A receptor rho1 subunit*ENSDARG0000009808126
gabrz / gamma-aminobutyric acid (GABA) A receptor, zetaENSDARG0000009451226
gabrr1 / gamma-aminobutyric acid (GABA) A receptor, rho 1 / P24046* / P56475* / Gamma-aminobutyric acid receptor subunit rho-1 * / gamma-aminobutyric acid type A receptor rho1 subunit*ENSDARG0000004390226
AL929217.1 / GABRP* / O00591* / gamma-aminobutyric acid type A receptor pi subunit*ENSDARG0000005989126
gabrr3a / gamma-aminobutyric acid (GABA) A receptor, rho 3a / A8MPY1* / GABRR3* / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene)*ENSDARG0000002715325
gabrr3b / gamma-aminobutyric acid (GABA) A receptor, rho 3b / A8MPY1* / GABRR3* / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene)*ENSDARG0000003075025
gabrb2 / gamma-aminobutyric acid (GABA) A receptor, beta 2 / P47870* / P63137* / Gamma-aminobutyric acid receptor subunit beta-2 * / gamma-aminobutyric acid type A receptor beta2 subunit*ENSDARG0000007958624


Protein motifs (from Interpro)
Interpro ID Name
 IPR006028  Gamma-aminobutyric acid A receptor/Glycine receptor alpha
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR008127  Glycine receptor alpha
 IPR018000  Neurotransmitter-gated ion-channel, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007218 neuropeptide signaling pathway IBA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0043200 response to amino acid IBA
 biological_processGO:0060012 synaptic transmission, glycinergic IBA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0098794 postsynapse IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0016594 glycine binding IBA
 molecular_functionGO:0016934 extracellularly glycine-gated chloride channel activity IBA
 molecular_functionGO:0022824 transmitter-gated ion channel activity IEA


Pathways (from Reactome)
Pathway description
Neurotransmitter receptors and postsynaptic signal transmission


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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