Manteia

ENSDARG00000076127

Danio rerio

Features

Gene ID:	ENSDARG00000076127

Biological name :	gabrb1

Synonyms :	gabrb1 / gamma-aminobutyric acid (GABA) A receptor, beta 1

Possible biological names infered from orthology :	Gamma-aminobutyric acid receptor subunit beta-1 / gamma-aminobutyric acid type A receptor beta1 subunit / P18505 / P50571

Species:	Danio rerio

Chr. number:	13
Strand:	1
Band:
Gene start:	12299997
Gene end:	12375593

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000097944 NCBI entrez gene - 100331377 See in Manteia. swissprot - F1QPW7 ZFIN ID - ZDB-GENE-090313-230 Ensembl - ENSDARG00000076127

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
GABRB1	ENSG00000163288	Homo sapiens
Gabrb1	ENSMUSG00000029212	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
gabrb3 / gamma-aminobutyric acid (GABA) A receptor, beta 3	ENSDARG00000023771	73
GABRB2 (1 of many) / gamma-aminobutyric acid type A receptor beta2 subunit / GABRB2* / P47870*	ENSDARG00000100032	70
gabrb4 / gamma-aminobutyric acid (GABA) A receptor, beta 4 / GABRQ* / Q9UN88* / Q9JLF1* / Gamma-aminobutyric acid receptor subunit theta * / gamma-aminobutyric acid type A receptor theta subunit*	ENSDARG00000099096	70
gabrb2 / gamma-aminobutyric acid (GABA) A receptor, beta 2 / P47870* / P63137* / Gamma-aminobutyric acid receptor subunit beta-2 * / gamma-aminobutyric acid type A receptor beta2 subunit*	ENSDARG00000079586	64
AL929217.1 / GABRP* / O00591* / gamma-aminobutyric acid type A receptor pi subunit*	ENSDARG00000059891	37
FO704905.1 / GABRR1* / P24046* / gamma-aminobutyric acid type A receptor rho1 subunit*	ENSDARG00000098081	36
gabrd / gamma-aminobutyric acid (GABA) A receptor, delta / O14764* / P22933* / Gamma-aminobutyric acid receptor subunit delta * / gamma-aminobutyric acid type A receptor delta subunit*	ENSDARG00000059763	35
gabrr1 / gamma-aminobutyric acid (GABA) A receptor, rho 1 / P24046* / P56475* / Gamma-aminobutyric acid receptor subunit rho-1 * / gamma-aminobutyric acid type A receptor rho1 subunit*	ENSDARG00000043902	35
gabrr2b / gamma-aminobutyric acid (GABA) A receptor, rho 2b / P56476* / GABRR2* / P28476* / Gamma-aminobutyric acid receptor subunit rho-2 * / gamma-aminobutyric acid type A receptor rho2 subunit*	ENSDARG00000014057	35
gabrz / gamma-aminobutyric acid (GABA) A receptor, zeta	ENSDARG00000094512	35
gabrp / gamma-aminobutyric acid (GABA) A receptor, pi	ENSDARG00000020901	35
gabrr3b / gamma-aminobutyric acid (GABA) A receptor, rho 3b / A8MPY1* / GABRR3* / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene)*	ENSDARG00000030750	34
glra2 / si:ch211-12n8.3	ENSDARG00000075012	34
gabrr3a / gamma-aminobutyric acid (GABA) A receptor, rho 3a / A8MPY1* / GABRR3* / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene)*	ENSDARG00000027153	34
glra4a / glycine receptor, alpha 4a / GLRA4* / Q5JXX5* / Q61603* / glycine receptor alpha 4* / Glycine receptor subunit alpha-4 *	ENSDARG00000006865	33
glra1 / O93430 / glycine receptor, alpha 1 / Q64018* / P23415* / Glycine receptor subunit alpha-1 *	ENSDARG00000012019	33
glrbb / glycine receptor, beta b / GLRB* / P48167* / P48168* / glycine receptor beta* / Glycine receptor subunit beta *	ENSDARG00000052769	32
glra4b / glycine receptor, alpha 4b / GLRA4* / Q5JXX5* / Q61603* / glycine receptor alpha 4* / Glycine receptor subunit alpha-4 *	ENSDARG00000058103	32
glra3 / glycine receptor, alpha 3	ENSDARG00000011066	32
gabrr2b / gabrr2a / gamma-aminobutyric acid (GABA) A receptor, rho 2a / GABRR2* / P28476* / P56476* / Gamma-aminobutyric acid receptor subunit rho-2 * / gamma-aminobutyric acid type A recep...	ENSDARG00000052982	31

Protein motifs (from Interpro)

Interpro ID	Name
IPR002289	Gamma-aminobutyric-acid A receptor, beta subunit
IPR006028	Gamma-aminobutyric acid A receptor/Glycine receptor alpha
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain
IPR006201	Neurotransmitter-gated ion-channel
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain
IPR018000	Neurotransmitter-gated ion-channel, conserved site

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006811	ion transport	IEA
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0034220	ion transmembrane transport	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:1902711	GABA-A receptor complex	IBA
molecular_function	GO:0004888	transmembrane signaling receptor activity	IEA
molecular_function	GO:0004890	GABA-A receptor activity	IEA
molecular_function	GO:0005216	ion channel activity	IEA
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity	IEA

Pathways (from Reactome)

Pathway description

GABA A receptor activation

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000076127	gabrb1 / gamma-aminobutyric acid (GABA) A receptor, beta 1 / P18505* / P50571* / Gamma-aminobutyric acid receptor subunit beta-1 * / gamma-aminobutyric acid type A receptor beta1 subunit*	/ complex
ENSDARG00000053665	gabrg2 / gamma-aminobutyric acid (GABA) A receptor, gamma 2 / P18507* / P22723* / Gamma-aminobutyric acid receptor subunit gamma-2 * / gamma-aminobutyric acid type A receptor gamma2 subunit*	/ complex
ENSDARG00000099096	gabrb4 / gamma-aminobutyric acid (GABA) A receptor, beta 4 / GABRQ* / Q9UN88* / Q9JLF1* / Gamma-aminobutyric acid receptor subunit theta * / gamma-aminobutyric acid type A receptor theta subunit*	/ complex

1 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr