ENSDARG00000079586


Danio rerio

Features
Gene ID: ENSDARG00000079586
  
Biological name :gabrb2
  
Synonyms : gabrb2 / gamma-aminobutyric acid (GABA) A receptor, beta 2
  
Possible biological names infered from orthology : Gamma-aminobutyric acid receptor subunit beta-2 / gamma-aminobutyric acid type A receptor beta2 subunit / P47870 / P63137
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 22172047
Gene end: 22273847
  
Corresponding Affymetrix probe sets: Dr.10676.2.S1_at (Zebrafish Array)   NM_001024387_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000104215
Ensembl peptide - ENSDARP00000114799
NCBI entrez gene - 336252     See in Manteia.
RefSeq - NM_001024387
RefSeq Peptide - NP_001019558
swissprot - F1R406
swissprot - E9QE94
ZFIN ID - ZDB-GENE-030131-8196
Ensembl - ENSDARG00000079586
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GABRB2ENSGALG00000001690Gallus gallus
 GABRB2ENSG00000145864Homo sapiens
 Gabrb2ENSMUSG00000007653Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GABRB2 (1 of many) / gamma-aminobutyric acid type A receptor beta2 subunit / GABRB2* / P47870*ENSDARG0000010003281
gabrb1 / gamma-aminobutyric acid (GABA) A receptor, beta 1 / P18505* / P50571* / Gamma-aminobutyric acid receptor subunit beta-1 * / gamma-aminobutyric acid type A receptor beta1 subunit*ENSDARG0000007612771
gabrb3 / gamma-aminobutyric acid (GABA) A receptor, beta 3ENSDARG0000002377170
gabrb4 / gamma-aminobutyric acid (GABA) A receptor, beta 4 / GABRQ* / Q9UN88* / Q9JLF1* / Gamma-aminobutyric acid receptor subunit theta * / gamma-aminobutyric acid type A receptor theta subunit*ENSDARG0000009909667
FO704905.1 / GABRR1* / P24046* / gamma-aminobutyric acid type A receptor rho1 subunit*ENSDARG0000009808134
gabrd / gamma-aminobutyric acid (GABA) A receptor, delta / O14764* / P22933* / Gamma-aminobutyric acid receptor subunit delta * / gamma-aminobutyric acid type A receptor delta subunit*ENSDARG0000005976333
glra2 / si:ch211-12n8.3ENSDARG0000007501232
gabrr2b / gamma-aminobutyric acid (GABA) A receptor, rho 2b / P56476* / GABRR2* / P28476* / Gamma-aminobutyric acid receptor subunit rho-2 * / gamma-aminobutyric acid type A receptor rho2 subunit*ENSDARG0000001405732
gabrz / gamma-aminobutyric acid (GABA) A receptor, zetaENSDARG0000009451232
AL929217.1 / GABRP* / O00591* / gamma-aminobutyric acid type A receptor pi subunit*ENSDARG0000005989132
gabrr2b / gabrr2a / gamma-aminobutyric acid (GABA) A receptor, rho 2a / GABRR2* / P28476* / P56476* / Gamma-aminobutyric acid receptor subunit rho-2 * / gamma-aminobutyric acid type A recep...ENSDARG0000005298232
gabrp / gamma-aminobutyric acid (GABA) A receptor, piENSDARG0000002090132
gabrr3b / gamma-aminobutyric acid (GABA) A receptor, rho 3b / A8MPY1* / GABRR3* / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene)*ENSDARG0000003075032
gabrr1 / gamma-aminobutyric acid (GABA) A receptor, rho 1 / P24046* / P56475* / Gamma-aminobutyric acid receptor subunit rho-1 * / gamma-aminobutyric acid type A receptor rho1 subunit*ENSDARG0000004390232
glra4a / glycine receptor, alpha 4a / GLRA4* / Q5JXX5* / Q61603* / glycine receptor alpha 4* / Glycine receptor subunit alpha-4 *ENSDARG0000000686531
gabrr3a / gamma-aminobutyric acid (GABA) A receptor, rho 3a / A8MPY1* / GABRR3* / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene)*ENSDARG0000002715331
glra1 / O93430 / glycine receptor, alpha 1 / Q64018* / P23415* / Glycine receptor subunit alpha-1 *ENSDARG0000001201931
glra3 / glycine receptor, alpha 3ENSDARG0000001106631
glra4b / glycine receptor, alpha 4b / GLRA4* / Q5JXX5* / Q61603* / glycine receptor alpha 4* / Glycine receptor subunit alpha-4 *ENSDARG0000005810329
glrbb / glycine receptor, beta b / GLRB* / P48167* / P48168* / glycine receptor beta* / Glycine receptor subunit beta *ENSDARG0000005276928


Protein motifs (from Interpro)
Interpro ID Name
 IPR002289  Gamma-aminobutyric-acid A receptor, beta subunit
 IPR006028  Gamma-aminobutyric acid A receptor/Glycine receptor alpha
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:1902711 GABA-A receptor complex IBA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004890 GABA-A receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA


Pathways (from Reactome)
Pathway description
GABA A receptor activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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