ENSDARG00000056557


Danio rerio

Features
Gene ID: ENSDARG00000056557
  
Biological name :copb1
  
Synonyms : coatomer protein complex, subunit beta 1 / copb1 / Q66HV4
  
Possible biological names infered from orthology : Coatomer subunit beta / P53618 / Q9JIF7
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 27802480
Gene end: 27820976
  
Corresponding Affymetrix probe sets: Dr.7126.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000073498
swissprot - Q66HV4
ZFIN ID - ZDB-GENE-030219-38
Ensembl - ENSDARG00000056557
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COPB1ENSGALG00000006015Gallus gallus
 COPB1ENSG00000129083Homo sapiens
 Copb1ENSMUSG00000030754Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002553  Clathrin/coatomer adaptor, adaptin-like, N-terminal
 IPR011710  Coatomer beta subunit, C-terminal
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR016460  Coatomer beta subunit (COPB1)
 IPR029446  Coatomer beta subunit, appendage platform domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IBA
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IBA
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0030903 notochord development IMP
 biological_processGO:0061053 somite development IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030117 membrane coat IEA
 cellular_componentGO:0030126 COPI vesicle coat IBA
 cellular_componentGO:0030663 COPI-coated vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005198 structural molecule activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000135 notochord notochord quality , abnormal
notochord undifferentiated , abnormal
notochord decreased length , abnormal
notochord apoptotic , abnormal
notochord basement membrane decreased thickness , abnormal
notochord basement membrane disorganized , abnormal
notochord basal lamina absent , abnormal
notochord endoplasmic reticulum swollen , abnormal
notochord Golgi apparatus structure , abnormal
notochord poorly differentiated , abnormal
Show

 ZFA:0000155 somite somite size , abnormal
somite condensed , abnormal
somite morphology , abnormal
Show

 ZFA:0001094 whole organism whole organism shape , abnormal
whole organism decreased length , abnormal
whole organism lethal (sensu genetics) , abnormal
whole organism viability , abnormal
Show

 ZFA:0001115 trunk trunk melanosome absent , abnormal
Show

 ZFA:0009091 melanocyte melanocyte melanosome absent , abnormal
Show

 ZFA:0009114 muscle cell muscle cell endoplasmic reticulum swollen , abnormal
muscle cell Golgi apparatus structure , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000019581 uso1 / USO1 vesicle transport factor / O60763* / Q9Z1Z0* / USO1 vesicle docking factor*  / reaction / complex
 ENSDARG00000002792 arcn1a / archain 1a / ARCN1* / P48444* / Q5XJY5* / archain 1* / Coatomer subunit delta *  / complex
 ENSDARG00000031214 arcn1b / archain 1b / ARCN1* / P48444* / Q5XJY5* / archain 1* / Coatomer subunit delta *  / complex
 ENSDARG00000027016 gbf1 / golgi brefeldin A resistant guanine nucleotide exchange factor 1 / Q92538*  / reaction / complex
 ENSDARG00000034823 copg2 / Q9PUE4 / coatomer protein complex, subunit gamma 2 / Q9QXK3* / Q9UBF2* / Coatomer subunit gamma-2 *  / complex






 

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