ENSG00000129083


Homo sapiens

Features
Gene ID: ENSG00000129083
  
Biological name :COPB1
  
Synonyms : coatomer protein complex subunit beta 1 / COPB1 / P53618
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p15.2
Gene start: 14443440
Gene end: 14500027
  
Corresponding Affymetrix probe sets: 201358_s_at (Human Genome U133 Plus 2.0 Array)   201359_at (Human Genome U133 Plus 2.0 Array)   233308_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000249923
Ensembl peptide - ENSP00000436401
Ensembl peptide - ENSP00000436383
Ensembl peptide - ENSP00000431530
Ensembl peptide - ENSP00000397873
NCBI entrez gene - 1315     See in Manteia.
OMIM - 600959
RefSeq - NM_001144061
RefSeq - NM_001144062
RefSeq - NM_016451
RefSeq Peptide - NP_001137534
RefSeq Peptide - NP_057535
RefSeq Peptide - NP_001137533
swissprot - P53618
swissprot - E9PP63
swissprot - E9PKQ1
swissprot - E9PP73
Ensembl - ENSG00000129083
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 copb1ENSDARG00000056557Danio rerio
 COPB1ENSGALG00000006015Gallus gallus
 Copb1ENSMUSG00000030754Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002553  Clathrin/coatomer adaptor, adaptin-like, N-terminal
 IPR011710  Coatomer beta subunit, C-terminal
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR016460  Coatomer beta subunit (COPB1)
 IPR029446  Coatomer beta subunit, appendage platform domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IBA
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005798 Golgi-associated vesicle TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030117 membrane coat IEA
 cellular_componentGO:0030126 COPI vesicle coat IBA
 cellular_componentGO:0030133 transport vesicle TAS
 cellular_componentGO:0030137 COPI-coated vesicle IEA
 cellular_componentGO:0030663 COPI-coated vesicle membrane IEA
 cellular_componentGO:0030667 secretory granule membrane TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070821 tertiary granule membrane TAS
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000122218 COPA / P53621 / coatomer protein complex subunit alpha  / complex
 ENSG00000168374 ARF4 / P18085 / ADP ribosylation factor 4  / complex / reaction
 ENSG00000095139 ARCN1 / P48444 / archain 1  / complex
 ENSG00000138768 USO1 / O60763 / USO1 vesicle transport factor  / complex / reaction
 ENSG00000105669 COPE / O14579 / coatomer protein complex subunit epsilon  / complex
 ENSG00000181789 COPG1 / Q9Y678 / coatomer protein complex subunit gamma 1  / complex
 ENSG00000158623 COPG2 / Q9UBF2 / coatomer protein complex subunit gamma 2  / complex
 ENSG00000107862 GBF1 / Q92538 / golgi brefeldin A resistant guanine nucleotide exchange factor 1  / reaction / complex
 ENSG00000005243 COPZ2 / Q9P299 / coatomer protein complex subunit zeta 2  / complex
 ENSG00000174903 RAB1B / Q9H0U4 / RAB1B, member RAS oncogene family  / complex / reaction
 ENSG00000111481 COPZ1 / P61923 / coatomer protein complex subunit zeta 1  / complex
 ENSG00000184432 COPB2 / P35606 / coatomer protein complex subunit beta 2  / complex






 

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