ENSG00000138768


Homo sapiens

Features
Gene ID: ENSG00000138768
  
Biological name :USO1
  
Synonyms : O60763 / USO1 / USO1 vesicle transport factor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q21.1
Gene start: 75724593
Gene end: 75814286
  
Corresponding Affymetrix probe sets: 201831_s_at (Human Genome U133 Plus 2.0 Array)   201832_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000444850
Ensembl peptide - ENSP00000264904
NCBI entrez gene - 8615     See in Manteia.
OMIM - 603344
RefSeq - XM_006714397
RefSeq - NM_001290049
RefSeq - NM_003715
RefSeq - XM_006714396
RefSeq Peptide - NP_003706
RefSeq Peptide - NP_001276978
swissprot - O60763
swissprot - A0A024RDG1
Ensembl - ENSG00000138768
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 uso1ENSDARG00000019581Danio rerio
 USO1ENSGALG00000010878Gallus gallus
 Uso1ENSMUSG00000029407Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR006953  Vesicle tethering protein Uso1/P115-like , head domain
 IPR006955  Uso1/p115-like vesicle tethering protein, C-terminal
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IEA
 biological_processGO:0007030 Golgi organization IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0045056 transcytosis IEA
 biological_processGO:0048208 COPII vesicle coating TAS
 biological_processGO:0048211 Golgi vesicle docking IBA
 biological_processGO:0048280 vesicle fusion with Golgi apparatus IEA
 biological_processGO:0061025 membrane fusion IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005795 Golgi stack IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0012507 ER to Golgi transport vesicle membrane TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030133 transport vesicle TAS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008565 protein transporter activity IBA
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
Golgi Cisternae Pericentriolar Stack Reorganization
COPII-mediated vesicle transport
COPI-mediated anterograde transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000108433 GOSR2 / O14653 / golgi SNAP receptor complex member 2  / reaction
 ENSG00000105829 BET1 / O15155 / Bet1 golgi vesicular membrane trafficking protein  / reaction
 ENSG00000129083 COPB1 / P53618 / coatomer protein complex subunit beta 1  / complex / reaction
 ENSG00000122218 COPA / P53621 / coatomer protein complex subunit alpha  / complex / reaction
 ENSG00000111481 COPZ1 / P61923 / coatomer protein complex subunit zeta 1  / reaction / complex
 ENSG00000184432 COPB2 / P35606 / coatomer protein complex subunit beta 2  / complex / reaction
 ENSG00000174903 RAB1B / Q9H0U4 / RAB1B, member RAS oncogene family  / reaction / complex
 ENSG00000176986 P53992 / SEC24C / SEC24 homolog C, COPII coat complex component  / complex / reaction
 ENSG00000005243 COPZ2 / Q9P299 / coatomer protein complex subunit zeta 2  / complex / reaction
 ENSG00000265808 O75396 / SEC22B / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)  / complex / reaction
 ENSG00000181789 COPG1 / Q9Y678 / coatomer protein complex subunit gamma 1  / complex / reaction
 ENSG00000113615 O95486 / SEC24A / SEC24 homolog A, COPII coat complex component  / complex / reaction
 ENSG00000138802 O95487 / SEC24B / SEC24 homolog B, COPII coat complex component  / reaction / complex
 ENSG00000157020 SEC13 / P55735 / SEC13 homolog, nuclear pore and COPII coat complex component  / reaction / complex
 ENSG00000105669 COPE / O14579 / coatomer protein complex subunit epsilon  / complex / reaction
 ENSG00000114745 Q9BQQ3 / GORASP1 / golgi reassembly stacking protein 1  / complex / reaction
 ENSG00000095139 ARCN1 / P48444 / archain 1  / complex / reaction
 ENSG00000168374 ARF4 / P18085 / ADP ribosylation factor 4  / complex / reaction
 ENSG00000138069 RAB1A / P62820 / RAB1A, member RAS oncogene family  / complex / reaction
 ENSG00000150961 O94855 / SEC24D / SEC24 homolog D, COPII coat complex component  / reaction / complex
 ENSG00000138674 O94979 / SEC31A / SEC31 homolog A, COPII coat complex component  / reaction / complex
 ENSG00000158623 COPG2 / Q9UBF2 / coatomer protein complex subunit gamma 2  / complex / reaction
 ENSG00000107651 Q9Y6Y8 / SEC23IP / SEC23 interacting protein  / complex / reaction
 ENSG00000138768 USO1 / O60763 / USO1 vesicle transport factor  / complex
 ENSG00000107862 GBF1 / Q92538 / golgi brefeldin A resistant guanine nucleotide exchange factor 1  / complex / reaction
 ENSG00000100934 Q15436 / SEC23A / Sec23 homolog A, coat complex II component  / complex / reaction
 ENSG00000167110 GOLGA2 / Q08379 / golgin A2  / reaction / complex
 ENSG00000134057 CCNB1 / P14635 / cyclin B1  / reaction
 ENSG00000162236 STX5 / Q13190 / syntaxin 5  / reaction
 ENSG00000141551 CSNK1D / P48730 / casein kinase 1 delta  / reaction
 ENSG00000157456 CCNB2 / O95067 / cyclin B2  / reaction
 ENSG00000092108 SCFD1 / Q8WVM8 / sec1 family domain containing 1  / reaction
 ENSG00000170312 CDK1 / P06493 / cyclin dependent kinase 1  / reaction






 

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