ENSG00000157456


Homo sapiens

Features
Gene ID: ENSG00000157456
  
Biological name :CCNB2
  
Synonyms : CCNB2 / cyclin B2 / O95067
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q22.2
Gene start: 59105078
Gene end: 59125045
  
Corresponding Affymetrix probe sets: 202705_at (Human Genome U133 Plus 2.0 Array)   232764_at (Human Genome U133 Plus 2.0 Array)   232768_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453685
Ensembl peptide - ENSP00000480809
Ensembl peptide - ENSP00000288207
NCBI entrez gene - 9133     See in Manteia.
OMIM - 602755
RefSeq - NM_004701
RefSeq Peptide - NP_004692
swissprot - O95067
swissprot - H0YMP3
swissprot - H1UBN3
Ensembl - ENSG00000157456
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccnb2ENSDARG00000036180Danio rerio
 CCNB2ENSGALG00000004161Gallus gallus
 Ccnb2ENSMUSG00000032218Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCNB1 / P14635 / cyclin B1ENSG0000013405754
CCNB3 / Q8WWL7 / cyclin B3ENSG0000014708229
CCNA1 / P78396 / cyclin A1ENSG0000013310128
CCNA2 / P20248 / cyclin A2ENSG0000014538628
CCNO / P22674 / cyclin OENSG0000015266919
CCNE1 / P24864 / cyclin E1ENSG0000010517319
CCNE2 / O96020 / cyclin E2ENSG0000017530519
CCND3 / P30281 / cyclin D3ENSG0000011257615
CCND2 / P30279 / cyclin D2ENSG0000011897113
CCND1 / P24385 / cyclin D1ENSG0000011009212


Protein motifs (from Interpro)
Interpro ID Name
 IPR004367  Cyclin, C-terminal domain
 IPR006671  Cyclin, N-terminal
 IPR013763  Cyclin-like
 IPR036915  Cyclin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007077 mitotic nuclear envelope disassembly TAS
 biological_processGO:0040007 growth IEA
 biological_processGO:0043029 T cell homeostasis IEA
 biological_processGO:0048538 thymus development IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051726 regulation of cell cycle TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
Polo-like kinase mediated events
Golgi Cisternae Pericentriolar Stack Reorganization
Resolution of Sister Chromatid Cohesion
Condensation of Prometaphase Chromosomes
Regulation of PLK1 Activity at G2/M Transition
Activation of NIMA Kinases NEK9, NEK6, NEK7
Nuclear Pore Complex (NPC) Disassembly
Cyclin A/B1/B2 associated events during G2/M transition
G2/M DNA replication checkpoint
The role of GTSE1 in G2/M progression after G2 checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000101224 CDC25B / P30305 / cell division cycle 25B  / reaction
 ENSG00000127564 PKMYT1 / Q99640 / protein kinase, membrane associated tyrosine/threonine 1  / reaction
 ENSG00000121892 PDS5A / Q29RF7 / PDS5 cohesin associated factor A  / reaction
 ENSG00000062650 WAPL / Q7Z5K2 / WAPL cohesin release factor  / reaction
 ENSG00000119638 NEK9 / Q8TD19 / NIMA related kinase 9  / reaction
 ENSG00000114745 Q9BQQ3 / GORASP1 / golgi reassembly stacking protein 1  / reaction
 ENSG00000167110 GOLGA2 / Q08379 / golgin A2  / reaction
 ENSG00000170312 CDK1 / P06493 / cyclin dependent kinase 1  / complex / reaction
 ENSG00000146670 CDCA5 / Q96FF9 / cell division cycle associated 5  / reaction
 ENSG00000138768 USO1 / O60763 / USO1 vesicle transport factor  / reaction
 ENSG00000136122 BORA / Q6PGQ7 / bora, aurora kinase A activator  / reaction
 ENSG00000138069 RAB1A / P62820 / RAB1A, member RAS oncogene family  / reaction
 ENSG00000083642 PDS5B / Q9NTI5 / PDS5 cohesin associated factor B  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr