ENSG00000083642


Homo sapiens

Features
Gene ID: ENSG00000083642
  
Biological name :PDS5B
  
Synonyms : PDS5B / PDS5 cohesin associated factor B / Q9NTI5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q13.1
Gene start: 32586427
Gene end: 32778019
  
Corresponding Affymetrix probe sets: 1554634_at (Human Genome U133 Plus 2.0 Array)   1570119_at (Human Genome U133 Plus 2.0 Array)   204742_s_at (Human Genome U133 Plus 2.0 Array)   207956_x_at (Human Genome U133 Plus 2.0 Array)   215888_at (Human Genome U133 Plus 2.0 Array)   242302_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000407005
Ensembl peptide - ENSP00000313851
Ensembl peptide - ENSP00000401619
NCBI entrez gene - 23047     See in Manteia.
OMIM - 605333
RefSeq - XM_017020453
RefSeq - NM_015032
RefSeq - XM_017020450
RefSeq - XM_017020451
RefSeq - XM_017020452
RefSeq - XM_005266298
RefSeq - XM_011534999
RefSeq - XM_011535000
RefSeq - XM_011535002
RefSeq - XM_017020448
RefSeq - XM_017020449
RefSeq Peptide - NP_055847
swissprot - Q9NTI5
swissprot - A9IYQ1
Ensembl - ENSG00000083642
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pds5bENSDARG00000098897Danio rerio
 PDS5BENSGALG00000017070Gallus gallus
 Pds5bENSMUSG00000034021Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDS5A / Q29RF7 / PDS5 cohesin associated factor AENSG0000012189263


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0007064 mitotic sister chromatid cohesion IMP
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0042127 regulation of cell proliferation IDA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000775 chromosome, centromeric region TAS
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005694 chromosome TAS
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding TAS


Pathways (from Reactome)
Pathway description
Separation of Sister Chromatids
Establishment of Sister Chromatid Cohesion
Cohesin Loading onto Chromatin
Resolution of Sister Chromatid Cohesion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000129933 MAU2 / Q9Y6X3 / MAU2 sister chromatid cohesion factor  / reaction / complex
 ENSG00000134057 CCNB1 / P14635 / cyclin B1  / reaction
 ENSG00000062650 WAPL / Q7Z5K2 / WAPL cohesin release factor  / complex / reaction
 ENSG00000164190 NIPBL / Q6KC79 / NIPBL, cohesin loading factor  / reaction / complex
 ENSG00000171320 ESCO2 / Q56NI9 / establishment of sister chromatid cohesion N-acetyltransferase 2  / reaction
 ENSG00000146670 CDCA5 / Q96FF9 / cell division cycle associated 5  / complex / reaction
 ENSG00000164754 RAD21 / O60216 / RAD21 cohesin complex component  / reaction
 ENSG00000157456 CCNB2 / O95067 / cyclin B2  / reaction
 ENSG00000166851 PLK1 / P53350 / polo like kinase 1  / reaction
 ENSG00000141446 ESCO1 / Q5FWF5 / establishment of sister chromatid cohesion N-acetyltransferase 1  / reaction
 ENSG00000121892 PDS5A / Q29RF7 / PDS5 cohesin associated factor A  / reaction
 ENSG00000083642 PDS5B / Q9NTI5 / PDS5 cohesin associated factor B  / reaction
 ENSG00000170312 CDK1 / P06493 / cyclin dependent kinase 1  / reaction






 

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